A Clinical and Pathological Overview of Vulvar Condyloma Acuminatum, Intraepithelial Neoplasia, and Squamous Cell Carcinoma

• Published in: BioMed research international Vol. 2014; no. 2014; pp. 1 - 11
• Main Authors: Léonard, Boris, Kridelka, Frederic, Delbecque, Katty, Goffin, Frederic, Demoulin, Stéphanie, Doyen, Jean, Delvenne, Philippe
• Format: Journal Article Web Resource
• Language: English
• Published: Cairo, Egypt Hindawi Puplishing Corporation 01.01.2014; Hindawi Publishing Corporation; Hindawi Limited; Hindawi
• Subjects: Biomedical research; Carcinoma in Situ - pathology; Carcinoma, Squamous Cell - pathology; Condylomata Acuminata - pathology; Dermatologie; Dermatology; Female; Human health sciences; Humans; Papillomaviridae - pathogenicity; Papillomavirus Infections - complications; Papillomavirus Infections - pathology; Papillomavirus Infections - virology; Precancerous Conditions - pathology; Precancerous Conditions - virology; Review; Sciences de la santé humaine; Vulvar Neoplasms - complications; Vulvar Neoplasms - pathology
• ISSN: 2314-6133; 2314-6141; 2314-6141
• DOI: 10.1155/2014/480573

Condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma are three relatively frequent vulvar lesions. Condyloma acuminatum is induced by low risk genotypes of human papillomavirus (HPV). Vulvar intraepithelial neoplasia (VIN) and squamous cell carcinoma have different etiopathogenic pathways and are related or not with high risk HPV types. The goal of this paper is to review the main pathological and clinical features of these lesions. A special attention has been paid also to epidemiological data, pathological classification, and clinical implications of these diseases.