Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation - Meng, Qiang; Duan, Xing-ping; Wang, Chang-yuan; Liu, Zhi-hao; Sun, Peng-yuan; Huo, Xiao-kui; Sun, Hui-jun; Peng, Jin-yong; Liu, Ke-xin (Acta pharmacologica Sinica, 2017)
Keywords: Animals; Biomedical and Life Sciences; Biomedicine; Chenodeoxycholic Acid - pharmacology; Cholestenones - antagonists & inhibitors; Cholestenones - pharmacology; Choline Deficiency; Dose-Response Relationship, Drug; Fibrosis - pathology; Gene Expression - drug effects; Hepatocytes - metabolism; Immunology; Internal Medicine; Lipid Metabolism - drug effects; Lipogenesis - drug effects; Liver - enzymology; Liver - metabolism; Liver - pathology; Male; Medical Microbiology; Methionine - deficiency; Mice; Non-alcoholic Fatty Liver Disease - prevention & control; Original; original-article; Pharmacology/Toxicology; Pregnenediones - pharmacology; Primary Cell Culture; Protective Agents - pharmacology; Receptors, Cytoplasmic and Nuclear - agonists; Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors; Vaccine; 受体拮抗剂; 法尼醇; 激活作用; 肝炎病毒; 脂肪合成; 荧光定量PCR; 酒精性; 醋酸; CDCA; hepatic inflammation; guggulsterone; alisol B 23-acetate; farnesoid X receptor; hepatic fibrosis; non-alcoholic steatohepatitis