Recent Update on PET/CT Radiotracers for Imaging Cerebral Glioma
Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering complementary insights to those gained through magnetic resonance imaging (MRI). PET/CT scans enable a multifaceted analysis of glioma biology, supporting clini...
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Published in | Nuclear medicine and molecular imaging Vol. 58; no. 4; pp. 237 - 245 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Singapore
Springer Nature Singapore
01.06.2024
Springer Nature B.V 대한핵의학회 |
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ISSN | 1869-3474 1869-3482 |
DOI | 10.1007/s13139-024-00847-4 |
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Abstract | Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering complementary insights to those gained through magnetic resonance imaging (MRI). PET/CT scans enable a multifaceted analysis of glioma biology, supporting clinical applications from grading and differential diagnosis to mapping the full extent of tumors and planning subsequent treatments and evaluations. With a broad array of specialized radiotracers, researchers and clinicians can now probe various biological characteristics of gliomas, such as glucose utilization, cellular proliferation, oxygen deficiency, amino acid trafficking, and reactive astrogliosis. This review aims to provide a recent update on the application of versatile PET/CT radiotracers in glioma research and clinical practice. |
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AbstractList | Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering complementary insights to those gained through magnetic resonance imaging (MRI). PET/CT scans enable a multifaceted analysis of glioma biology, supporting clinical applications from grading and differential diagnosis to mapping the full extent of tumors and planning subsequent treatments and evaluations. With a broad array of specialized radiotracers, researchers and clinicians can now probe various biological characteristics of gliomas, such as glucose utilization, cellular proliferation, oxygen deficiency, amino acid trafficking, and reactive astrogliosis. This review aims to provide a recent update on the application of versatile PET/CT radiotracers in glioma research and clinical practice. Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering complementary insights to those gained through magnetic resonance imaging (MRI). PET/CT scans enable a multifaceted analysis of glioma biology, supporting clinical applications from grading and differential diagnosis to mapping the full extent of tumors and planning subsequent treatments and evaluations. With a broad array of specialized radiotracers, researchers and clinicians can now probe various biological characteristics of gliomas, such as glucose utilization, cellular proliferation, oxygen deficiency, amino acid trafficking, and reactive astrogliosis. This review aims to provide a recent update on the application of versatile PET/CT radiotracers in glioma research and clinical practice.Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering complementary insights to those gained through magnetic resonance imaging (MRI). PET/CT scans enable a multifaceted analysis of glioma biology, supporting clinical applications from grading and differential diagnosis to mapping the full extent of tumors and planning subsequent treatments and evaluations. With a broad array of specialized radiotracers, researchers and clinicians can now probe various biological characteristics of gliomas, such as glucose utilization, cellular proliferation, oxygen deficiency, amino acid trafficking, and reactive astrogliosis. This review aims to provide a recent update on the application of versatile PET/CT radiotracers in glioma research and clinical practice. Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive gliomaevaluation, offering complementary insights to those gained through magnetic resonance imaging (MRI). PET/CT scansenable a multifaceted analysis of glioma biology, supporting clinical applications from grading and differential diagnosisto mapping the full extent of tumors and planning subsequent treatments and evaluations. With a broad array of specializedradiotracers, researchers and clinicians can now probe various biological characteristics of gliomas, such as glucose utilization,cellular proliferation, oxygen deficiency, amino acid trafficking, and reactive astrogliosis. This review aims to providea recent update on the application of versatile PET/CT radiotracers in glioma research and clinical practice. KCI Citation Count: 9 |
Author | Kim, Sun Jung Yun, Mijin Hwang, Hee Sung Kim, Dongwoo Lee, Suk-Hyun |
Author_xml | – sequence: 1 givenname: Dongwoo surname: Kim fullname: Kim, Dongwoo organization: Department of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine – sequence: 2 givenname: Suk-Hyun surname: Lee fullname: Lee, Suk-Hyun organization: Department of Radiology, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine – sequence: 3 givenname: Hee Sung surname: Hwang fullname: Hwang, Hee Sung organization: Department of Nuclear Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine – sequence: 4 givenname: Sun Jung surname: Kim fullname: Kim, Sun Jung organization: Department of Nuclear Medicine, National Health Insurance Service Ilsan Hospital – sequence: 5 givenname: Mijin surname: Yun fullname: Yun, Mijin email: yunmijin@yuhs.ac organization: Department of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine |
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Keywords | C-acetate F-FLT Amino acid radiotracer F-FMISO Glioma F-FDG 18F-FLT 11C-acetate 18F-FDG 18F-FMISO |
Language | English |
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Snippet | Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering complementary... Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive gliomaevaluation, offering complementary... |
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SubjectTerms | Amino acids Cardiology Computed tomography Imaging Magnetic resonance imaging Medical imaging Medicine Medicine & Public Health Nuclear Medicine Oncology Orthopedics Positron emission Radioactive tracers Radiology Review 방사선과학 |
Title | Recent Update on PET/CT Radiotracers for Imaging Cerebral Glioma |
URI | https://link.springer.com/article/10.1007/s13139-024-00847-4 https://www.ncbi.nlm.nih.gov/pubmed/38932755 https://www.proquest.com/docview/3071987805 https://www.proquest.com/docview/3072815093 https://pubmed.ncbi.nlm.nih.gov/PMC11196511 https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART003107671 |
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ispartofPNX | Nuclear Medicine and Molecular Imaging , 2024, 58(4), , pp.237-245 |
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