Structure and Mechanistic Analysis of the Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5 in Complex with Its gp41 Epitope

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Published inJournal of Virology Vol. 78; no. 19; pp. 10724 - 10737
Main Authors OFEK, Gilad, MIN TANG, SAMBOR, Anna, KATINGER, Hermann, MASCOLA, John R, WYATT, Richard, KWONG, Peter D
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.10.2004
Subjects
Amino Acid Sequence
Biological and medical sciences
Complementarity Determining Regions - chemistry
Crystallography, X-Ray
Epitopes - chemistry
Epitopes - immunology
Epitopes - metabolism
Fundamental and applied biological sciences. Psychology
HIV Antibodies - chemistry
HIV Antibodies - immunology
HIV Antibodies - metabolism
HIV Envelope Protein gp41 - chemistry
HIV Envelope Protein gp41 - immunology
HIV-1 - immunology
Human immunodeficiency virus 1
Human viral diseases
Humans
Infectious diseases
Medical sciences
Microbiology
Miscellaneous
Models, Molecular
Molecular Sequence Data
Neutralization Tests
Protein Binding
Protein Structure, Quaternary
Vaccines and Antiviral Agents
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Virology
Human
Immunopathology
Antigenic determinant
Microbiology
HIV-1 virus
Antibody
Retroviridae
AIDS
Lentivirus
Immune deficiency
Virology
Infection
Virus
Viral disease
Human immunodeficiency virus
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Summary:Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue JVI About JVI Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JVI RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0022-538X Online ISSN: 1098-5514 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to JVI .asm.org, visit: JVI       
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Corresponding author. Mailing address: Vaccine Research Center, NIAID/NIH, 40 Convent Dr., Building 40, Room 4508, Bethesda, MD 20892. Phone: (301) 594-8439. Fax: (301) 480-0274. E-mail: pdkwong@nih.gov.
ISSN:0022-538X
1098-5514
DOI:10.1128/JVI.78.19.10724-10737.2004