Integrated electrical concentration and lysis of cells in a microfluidic chip

• Published in: Biomicrofluidics Vol. 4; no. 4; pp. 44101 - 44110
• Main Authors: Church, Christopher, Zhu, Junjie, Huang, Guohui, Tzeng, Tzuen-Rong, Xuan, Xiangchun
• Format: Journal Article
• Language: English
• Published: United States American Institute of Physics 01.10.2010
• Subjects: Regular

Lysing cells is an important step in the analysis of intracellular contents. Concentrating cells is often required in order to acquire adequate cells for lysis. This work presents an integrated concentration and lysis of mammalian cells in a constriction microchannel using dc-biased ac electric fiel...