Volatile aldehydes in the mainstream smoke of the narghile waterpipe
Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking has become popular all over the world. This study is concerned with the identification and quantification of volatile aldehydes in the gas an...
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| Published in | Food and chemical toxicology Vol. 46; no. 11; pp. 3546 - 3549 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Oxford
Elsevier Ltd
01.11.2008
Elsevier |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking has become popular all over the world. This study is concerned with the identification and quantification of volatile aldehydes in the gas and particle phases of mainstream narghile smoke generated using a popular type of flavored
ma’ssel tobacco mixture. These compounds were analyzed based on a modified version of the Environmental Protection Agency compendium method TO-11A. Using a standardized smoking machine protocol consisting of 171 puffs, 2.6
s puff duration and 17
s inter puff interval, the average yields of formaldehyde, acetaldehyde, acrolein, propionaldehyde and methacrolein were 630, 2520, 892, 403, and 106
μg/smoking session, respectively. The results showed that none of the aldehydes identified in this study are found in the particulate phase of the smoke, except for formaldehyde for which the partitioning coefficient was estimated as
K
p
=
3.3
×
10
−8
μg/m
3. Given previously reported lung absorption fractions of circa 90% for volatile aldehydes, the yields measured in this study are sufficient to induce various diseases depending on the extent of exposure, and on the breathing patterns of the smokers. |
|---|---|
| AbstractList | Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking has become popular all over the world. This study is concerned with the identification and quantification of volatile aldehydes in the gas and particle phases of mainstream narghile smoke generated using a popular type of flavored ma'ssel tobacco mixture. These compounds were analyzed based on a modified version of the Environmental Protection Agency compendium method TO-11A. Using a standardized smoking machine protocol consisting of 171 puffs, 2.6s puff duration and 17s inter puff interval, the average yields of formaldehyde, acetaldehyde, acrolein, propionaldehyde and methacrolein were 630, 2520, 892, 403, and 106 microg/smoking session, respectively. The results showed that none of the aldehydes identified in this study are found in the particulate phase of the smoke, except for formaldehyde for which the partitioning coefficient was estimated as Kp = 3.3 x 10(-8) microg/m3. Given previously reported lung absorption fractions of circa 90% for volatile aldehydes, the yields measured in this study are sufficient to induce various diseases depending on the extent of exposure, and on the breathing patterns of the smokers.Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking has become popular all over the world. This study is concerned with the identification and quantification of volatile aldehydes in the gas and particle phases of mainstream narghile smoke generated using a popular type of flavored ma'ssel tobacco mixture. These compounds were analyzed based on a modified version of the Environmental Protection Agency compendium method TO-11A. Using a standardized smoking machine protocol consisting of 171 puffs, 2.6s puff duration and 17s inter puff interval, the average yields of formaldehyde, acetaldehyde, acrolein, propionaldehyde and methacrolein were 630, 2520, 892, 403, and 106 microg/smoking session, respectively. The results showed that none of the aldehydes identified in this study are found in the particulate phase of the smoke, except for formaldehyde for which the partitioning coefficient was estimated as Kp = 3.3 x 10(-8) microg/m3. Given previously reported lung absorption fractions of circa 90% for volatile aldehydes, the yields measured in this study are sufficient to induce various diseases depending on the extent of exposure, and on the breathing patterns of the smokers. Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking has become popular all over the world. This study is concerned with the identification and quantification of volatile aldehydes in the gas and particle phases of mainstream narghile smoke generated using a popular type of flavored ma’ssel tobacco mixture. These compounds were analyzed based on a modified version of the Environmental Protection Agency compendium method TO-11A. Using a standardized smoking machine protocol consisting of 171 puffs, 2.6 s puff duration and 17 s inter puff interval, the average yields of formaldehyde, acetaldehyde, acrolein, propionaldehyde and methacrolein were 630, 2520, 892, 403, and 106 μg/smoking session, respectively. The results showed that none of the aldehydes identified in this study are found in the particulate phase of the smoke, except for formaldehyde for which the partitioning coefficient was estimated as K p = 3.3 × 10 -8 μg/m 3 . Given previously reported lung absorption fractions of circa 90% for volatile aldehydes, the yields measured in this study are sufficient to induce various diseases depending on the extent of exposure, and on the breathing patterns of the smokers. Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking has become popular all over the world. This study is concerned with the identification and quantification of volatile aldehydes in the gas and particle phases of mainstream narghile smoke generated using a popular type of flavored ma'ssel tobacco mixture. These compounds were analyzed based on a modified version of the Environmental Protection Agency compendium method TO-11A. Using a standardized smoking machine protocol consisting of 171 puffs, 2.6s puff duration and 17s inter puff interval, the average yields of formaldehyde, acetaldehyde, acrolein, propionaldehyde and methacrolein were 630, 2520, 892, 403, and 106 microg/smoking session, respectively. The results showed that none of the aldehydes identified in this study are found in the particulate phase of the smoke, except for formaldehyde for which the partitioning coefficient was estimated as Kp = 3.3 x 10(-8) microg/m3. Given previously reported lung absorption fractions of circa 90% for volatile aldehydes, the yields measured in this study are sufficient to induce various diseases depending on the extent of exposure, and on the breathing patterns of the smokers. Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking has become popular all over the world. This study is concerned with the identification and quantification of volatile aldehydes in the gas and particle phases of mainstream narghile smoke generated using a popular type of flavored ma’ssel tobacco mixture. These compounds were analyzed based on a modified version of the Environmental Protection Agency compendium method TO-11A. Using a standardized smoking machine protocol consisting of 171 puffs, 2.6 s puff duration and 17 s inter puff interval, the average yields of formaldehyde, acetaldehyde, acrolein, propionaldehyde and methacrolein were 630, 2520, 892, 403, and 106 μg/smoking session, respectively. The results showed that none of the aldehydes identified in this study are found in the particulate phase of the smoke, except for formaldehyde for which the partitioning coefficient was estimated as K p = 3.3 × 10 −8 μg/m 3. Given previously reported lung absorption fractions of circa 90% for volatile aldehydes, the yields measured in this study are sufficient to induce various diseases depending on the extent of exposure, and on the breathing patterns of the smokers. Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking has become popular all over the world. This study is concerned with the identification and quantification of volatile aldehydes in the gas and particle phases of mainstream narghile smoke generated using a popular type of flavored ma'ssel tobacco mixture. These compounds were analyzed based on a modified version of the Environmental Protection Agency compendium method TO-11A. Using a standardized smoking machine protocol consisting of 171 puffs, 2.6s puff duration and 17s inter puff interval, the average yields of formaldehyde, acetaldehyde, acrolein, propionaldehyde and methacrolein were 630, 2520, 892, 403, and 106kg/smoking session, respectively. The results showed that none of the aldehydes identified in this study are found in the particulate phase of the smoke, except for formaldehyde for which the partitioning coefficient was estimated as K sub(p)=3.3x10 super(-) super(8)kg /m super(3). Given previously reported lung absorption fractions of circa 90% for volatile aldehydes, the yields measured in this study are sufficient to induce various diseases depending on the extent of exposure, and on the breathing patterns of the smokers. |
| Author | Al Rashidi, M. Shihadeh, A. Saliba, N.A. |
| AuthorAffiliation | b Aerosol Research Lab, Department of Mechanical Engineering, American University of Beirut, Riad El Solh, Beirut, Lebanon a Department of Chemistry, American University of Beirut, Riad El Solh, Beirut, Lebanon |
| AuthorAffiliation_xml | – name: a Department of Chemistry, American University of Beirut, Riad El Solh, Beirut, Lebanon – name: b Aerosol Research Lab, Department of Mechanical Engineering, American University of Beirut, Riad El Solh, Beirut, Lebanon |
| Author_xml | – sequence: 1 givenname: M. surname: Al Rashidi fullname: Al Rashidi, M. organization: Department of Chemistry, American University of Beirut, Riad El Solh, Beirut, Lebanon – sequence: 2 givenname: A. surname: Shihadeh fullname: Shihadeh, A. organization: Aerosol Research Lab, Department of Mechanical Engineering, American University of Beirut, Riad El Solh, Beirut, Lebanon – sequence: 3 givenname: N.A. surname: Saliba fullname: Saliba, N.A. email: ns30@aub.edu.lb organization: Department of Chemistry, American University of Beirut, Riad El Solh, Beirut, Lebanon |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20887406$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/18834915$$D View this record in MEDLINE/PubMed |
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| Keywords | DNPH LPM IARC ACN Aldehyde Mainstream smoke TSP CARB Partitioning PAH EPA Health hazards HPLC Waterpipe COPD WHO Tobacco Health Toxicity Public health Narghile |
| Language | English |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Corresponding author. Tel.: +961 1 350000; fax: +961 1 365217. E-mail address: ns30@aub.edu.lb (N.A. Saliba). |
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| Snippet | Very little is known about the quality and quantity of toxicants yielded by the narghile, a subject of increasing importance as this method of tobacco smoking... |
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| SubjectTerms | Aldehyde Aldehydes - analysis Aldehydes - toxicity Biological and medical sciences Carcinogens - analysis Carcinogens - toxicity Chromatography, High Pressure Liquid - methods Health hazards Hot Temperature Mainstream smoke Medical sciences Partitioning Smoke - analysis Smoking - metabolism Tobacco Products Tobacco, tobacco smoking Toxicology Volatilization Waterpipe |
| Title | Volatile aldehydes in the mainstream smoke of the narghile waterpipe |
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