Differences in the Concentration of the Fecal Neurotransmitters GABA and Glutamate Are Associated with Microbial Composition among Healthy Human Subjects

• Published in: Microorganisms (Basel) Vol. 9; no. 2; p. 378
• Main Authors: Altaib, Hend, Nakamura, Kohei, Abe, Mayuko, Badr, Yassien, Yanase, Emiko, Nomura, Izumi, Suzuki, Tohru
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 13.02.2021; MDPI AG
• Subjects: Bifidobacterium; biomarkers; central nervous system; feces; GABA; gamma-aminobutyric acid; glutamic acid; gut microbiota; gut–brain axis; high performance liquid chromatography; humans; intestinal microorganisms; microbiome; neurotransmitters; probiotics; ribosomal RNA; serotonin; species diversity; GABA; Bifidobacterium; gut–brain axis; neurotransmitters; gut microbiota

Recent studies have shown that the gut microbiota modulates the physical and psychological functions of the host through several modes of action. One of them is mediating the production of active neurotransmitters, such as serotonin and gamma-aminobutyric acid (GABA). GABA is the major inhibitory ne...