The Influence of Particle Size Distribution and Surface Roughness of Carrier Particles on the in vitro Properties of Dry Powder Inhalations

• Published in: Aerosol science and technology Vol. 31; no. 4; pp. 301 - 321
• Main Author: Podczeck, Fridrun
• Format: Journal Article
• Language: English
• Published: London Taylor & Francis Group 01.10.1999; Taylor & Francis
• Subjects: Biological and medical sciences; Medical sciences; Pharmacology. Drug treatments; Respiratory system; Particle size; Xinafoate; Bronchodilator; Roughness; Salmeterol; Mixture; Powder; Inhalation; Lactose; Fine particle; Preparation; Distribution; Aerosols; Surface properties; Aerodynamic characteristic; Preconditioning; Vector; Hydrates

The influence of the amount of fine carrier particles, the shape of the particle size distributions, and the surface roughness of the coarse carrier particles on the aerodynamic properties of interactive powder mixtures from Salmeterol Xinafoate and lactose monohydrate have been investigated. In a f...