Gene expression alterations of human liver cancer cells following borax exposure

• Published in: Oncology reports Vol. 42; no. 1; pp. 115 - 130
• Main Authors: Wu, Lun, Wei, Ying, Zhou, Wen‑Bo, Zhang, You‑Shun, Chen, Qin‑Hua, Liu, Ming‑Xing, Zhu, Zheng‑Peng, Zhou, Jiao, Yang, Li‑Hua, Wang, Hong‑Mei, Wei, Guang‑Min, Wang, Sheng, Tang, Zhi‑Gang
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.07.2019; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Antioxidants (Nutrients); Biochemistry; Borates - pharmacology; Boron; Cancer; Cancer cells; Cancer genetics; Cell growth; Cell Proliferation - drug effects; Chemokines; Cytokines; Gene expression; Gene Expression Profiling - methods; Gene Expression Regulation, Neoplastic - drug effects; Gene Regulatory Networks - drug effects; Genes; Genetic aspects; Health aspects; Hep G2 Cells; Humans; Hybridization; Kinases; Ligands; Lipid peroxidation; Liver cancer; Liver Neoplasms - drug therapy; Liver Neoplasms - genetics; Oligonucleotide Array Sequence Analysis; Phosphatase; Polymerase chain reaction; Polypeptides; Proteins; Retirement benefits; Scientific equipment industry; Software; Transcription (Genetics); Transcription factors; Tumor necrosis factor-TNF; United States; China; United States > US

Borax is a boron compound that is becoming widely recognized for its biological effects, including lipid peroxidation, cytotoxicity, genotoxicity, antioxidant activity and potential therapeutic benefits. However, it remains unknown whether exposure of human liver cancer (HepG2) cells to borax affect...