Long-term outcomes of salvage high-dose-rate brachytherapy for localized recurrence of prostate cancer following definitive radiation therapy: a retrospective analysis

• Published in: BMC cancer Vol. 25; no. 1; pp. 524 - 11
• Main Authors: Watanabe, Kenta, Kamitani, Nobuhiko, Ikeda, Naoki, Kawata, Yujiro, Tokiya, Ryoji, Hayashi, Takafumi, Miyaji, Yoshiyuki, Tamada, Tsutomu, Katsui, Kuniaki
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 22.03.2025; BioMed Central; BMC
• Subjects: Adverse events; Aged; Aged, 80 and over; Analysis; Antigens; Biopsy; Brachytherapy; Brachytherapy - adverse effects; Brachytherapy - methods; Cancer; Cancer therapies; Care and treatment; CT imaging; Development and progression; Disease control; Dose; Dosimetry; Follow-Up Studies; High; Humans; Magnetic resonance imaging; Male; Metastasis; Middle Aged; Neoplasm Recurrence, Local - mortality; Neoplasm Recurrence, Local - pathology; Neoplasm Recurrence, Local - radiotherapy; Patient outcomes; Patients; Planning; Prostate cancer; Prostatic Neoplasms - mortality; Prostatic Neoplasms - pathology; Prostatic Neoplasms - radiotherapy; Radiation therapy; Radioisotope brachytherapy; Radiotherapy; Radiotherapy Dosage; Rate brachytherapy; Regression analysis; Relapse; Retrospective Studies; Salvage therapy; Salvage Therapy - adverse effects; Salvage Therapy - methods; Scintigraphy; Survival; Tomography; Toxicity; Treatment Outcome; Ultrasonic imaging; X-rays; Japan; High; Androgen deprivation therapy; Toxicity; Local recurrence; Term outcomes; Radiation therapy; Biochemical recurrence; Salvage therapy; Rate brachytherapy; Specific survival; Cause; Long; Dose; Prostate cancer

Salvage high-dose-rate brachytherapy (HDR-BT) is a potential treatment for localized recurrence of prostate cancer following definitive radiation therapy. This study aimed to evaluate the long-term safety and efficacy of HDR-BT alone, without androgen deprivation therapy (ADT), in this patient popul...