Structures of the Human HCN1 Hyperpolarization-Activated Channel - Lee, Chia-Hsueh; MacKinnon, Roderick (Cell, 2017)
Keywords: Amino Acid Sequence; amino acids; atomic structure; cardiac and neuronal pacemaker; cryo-electron microscopy; Cryoelectron Microscopy - methods; cyclic AMP; Cyclic AMP - chemistry; Cyclic AMP - metabolism; cytoplasm; heart rate; Humans; hydrogen cyanide; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - chemistry; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - metabolism; hyperpolarization-activated ion channel; ion selectivity; Models, Molecular; nerve tissue; neurons; permeability; potassium; potassium channels; Potassium Channels - chemistry; Potassium Channels - metabolism; rhythmic firing; Sequence Alignment; sodium; voltage-dependent gating; atomic structure; rhythmic firing; ion selectivity; cardiac and neuronal pacemaker; voltage-dependent gating; hyperpolarization-activated ion channel; cryo-electron microscopy