Intracranial Hemorrhage in a Young Woman: An Unusual Initial Presentation of Undiagnosed Choriocarcinoma

• Published in: Journal of neurosciences in rural practice Vol. 10; no. 2; pp. 371 - 373
• Main Authors: Agarwal, Navneet, Jain, S. K., Sharma, Vinod, Singhvi, Shashi, Gandhi, Sapna
• Format: Journal Article
• Language: English
• Published: A-12, Second Floor, Sector -2, NOIDA -201301, India Thieme Medical and Scientific Publishers Private Ltd 01.04.2019; Wolters Kluwer India Pvt. Ltd; Medknow Publications and Media Pvt. Ltd; Thieme Medical Publishers Inc; Wolters Kluwer - Medknow
• Subjects: Abdomen; Blood clots; Brain; Cancer; Care and treatment; Case Report; Chemotherapy; Choriocarcinoma; Diagnosis; Females; Health aspects; Hemorrhage; Medical research; Medicine, Experimental; Metastasis; Neurosurgery; NMR; Nuclear magnetic resonance; Pregnancy; Radiation therapy; Women; India; Beta-human chorionic gonadotropin; initially presenting; intracranial hemorrhage; choriocarcinoma
• ISSN: 0976-3147; 0976-3155
• DOI: 10.4103/jnrp.jnrp_307_18

ABSTRACT Choriocarcinoma is an uncommon tumor. Undiagnosed choriocarcinoma initially presenting with intracranial hemorrhage in an apparently healthy female is rare and presents a diagnostic difficulty. The authors report a case presenting as intracranial hemorrhage of unsuspected choriocarcinoma. As the measurement of beta-human chorionic gonadotropin (β-hCG) would have helped in the preoperative diagnosis, estimation of serum β-hCG levels is suggested in the diagnostic workup of a female of reproductive age group when radiological investigations are inconclusive. Craniotomy and excision of tumor followed by chemotherapy and radiotherapy may improve the outcome.