Obese Adolescents Show Impaired Meal Responses of the Appetite-Regulating Hormones Ghrelin and PYY

• Published in: Obesity (Silver Spring, Md.) Vol. 18; no. 5; pp. 918 - 925
• Main Authors: Mittelman, Steven D, Klier, Katie, Braun, Sharon, Azen, Colleen, Geffner, Mitchell E, Buchanan, Thomas A
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.05.2010
• Subjects: Adolescent; adolescents; Appetite; Area Under Curve; Blood Glucose; Calories; Child; Diabetes; Eating - physiology; Endocrinology; energy intake; Female; ghrelin; Ghrelin - blood; Hispanic people; Hispanics; Hormones; Humans; hunger; Insulin - blood; Male; Meals; Neuropeptides; Obesity; Obesity - blood; Obesity - physiopathology; peptide YY; Peptide YY - blood; Peptides; Physiology; Postprandial Period - physiology; Sandwiches; satiety; Satiety Response; Teenagers; Weight control; youth; Los Angeles California; United States > US; California

Ghrelin and peptide YY (PYY) stimulate hunger and satiety, respectively. The physiology of these hormones during normal meal intake remains unclear. This study was designed to compare the responses of these two hormones to meal intake between lean and obese Hispanic adolescents. A total of 10 obese...