25-Hydroxyvitamin D Deficiency Is Associated With Inflammation-Linked Vascular Endothelial Dysfunction in Middle-Aged and Older Adults - Jablonski, Kristen L.; Chonchol, Michel; Pierce, Gary L.; Walker, Ashley E.; Seals, Douglas R. (Hypertension (Dallas, Tex. 1979), 2011)
Keywords: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - analysis; Aged; Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Blood vessels and receptors; Brachial Artery - physiopathology; Cardiology. Vascular system; Endothelium, Vascular - drug effects; Endothelium, Vascular - physiopathology; Female; Fundamental and applied biological sciences. Psychology; Humans; Inflammation - metabolism; Inflammation - physiopathology; Interleukin-6 - analysis; Male; Medical sciences; Middle Aged; NF-kappa B - analysis; NF-kappa B - antagonists & inhibitors; Nitroglycerin - pharmacology; Receptors, Calcitriol - analysis; Salicylates - pharmacology; Vascular Diseases - etiology; Vascular Diseases - metabolism; Vasodilation - drug effects; Vasodilation - physiology; Vertebrates: cardiovascular system; Vitamin D - analogs & derivatives; Vitamin D - blood; Vitamin D - metabolism; Vitamin D Deficiency - complications; Vitamin D Deficiency - metabolism; Hypertension; endothelium-dependent dilation; Senescence; NFκB; Enzyme; VDR; Deficiency; Hydroxylase; Cardiovascular disease; Inflammation; interleukin-6; Endothelium; Interleukin 6; Oxidoreductases; aging; 1-α hydroxylase