DNA damage‐induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation - Oda, Tsukasa; Gotoh, Nanami; Kasamatsu, Tetsuhiro; Handa, Hiroshi; Saitoh, Takayuki; Sasaki, Nobuo (Cell proliferation, 2023)
Keywords: Accumulation; Age; Age related diseases; Antibodies; Antitumor agents; Apoptosis; Cell cycle; Cell Nucleus - metabolism; Cellular Senescence; Cellular stress response; Damage accumulation; Deoxyribonucleic acid; DNA; DNA Damage; DNA Repair; Foci; Gene expression; Genotoxicity; Humans; Intracellular Signaling Peptides and Proteins - genetics; Intracellular Signaling Peptides and Proteins - metabolism; Kinases; Liquid phases; Original; p53 Protein; Phase separation; Phosphorylation; Plasmids; Proteins; Senescence; Signal transduction; Signaling; siRNA; Stresses; Tumor suppressor genes; Tumor Suppressor p53-Binding Protein 1 - genetics; Tumor Suppressor p53-Binding Protein 1 - metabolism; Tumor Suppressor Protein p53 - metabolism; Tumors; Ubiquitin-Protein Ligases - genetics; Ubiquitin-Protein Ligases - metabolism; Yeast