Reactive oxygen species in cancer: Current findings and future directions

• Published in: Cancer science Vol. 112; no. 10; pp. 3945 - 3952
• Main Authors: Nakamura, Hajime, Takada, Kohichi
• Format: Journal Article
• Language: English
• Published: Tokyo John Wiley & Sons, Inc 01.10.2021; John Wiley and Sons Inc
• Subjects: Angiogenesis; Antigens; Antioxidants; Apoptosis; Cancer; Cancer therapies; Cell death; Cell growth; Cell migration; Cell proliferation; Colorectal cancer; Cytochrome; DNA damage; Enzymes; Hepatitis; Homeostasis; Hydrogen peroxide; Immunotherapy; Kinases; Lipids; Metabolism; Mitochondria; Molecular modelling; neoplasms; Organelles; Oxidants; Oxidative stress; Phosphorylation; Proteins; Radiation; Reactive oxygen species; Review; therapeutics

Reactive oxygen species (ROS), a class of highly bioactive molecules, have been widely studied in various types of cancers. ROS are considered to be normal byproducts of numerous cellular processes. Typically, cancer cells exhibit higher basal levels of ROS compared with normal cells as a result of...