Individual‐specific functional connectome biomarkers predict schizophrenia positive symptoms during adolescent brain maturation

• Published in: Human brain mapping Vol. 42; no. 5; pp. 1475 - 1484
• Main Authors: Fan, Yun‐Shuang, Li, Liang, Peng, Yue, Li, Haoru, Guo, Jing, Li, Meiling, Yang, Siqi, Yao, Meng, Zhao, Jingping, Liu, Hesheng, Liao, Wei, Guo, Xiaonan, Han, Shaoqiang, Cui, Qian, Duan, Xujun, Xu, Yong, Zhang, Yan, Chen, Huafu
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.04.2021
• Subjects: Adolescence; adolescent; Adolescents; Anatomy; Antipsychotics; Biological markers; biomarker; Biomarkers; Brain; Brain architecture; Brain mapping; Child psychopathology; Domains; functional connectome; Hypotheses; individual level; Maturation; Medical research; Medicine, Experimental; Mental disorders; Prediction models; Psychotropic drugs; Schizophrenia; Signs and symptoms; adolescent; schizophrenia; biomarker; functional connectome; individual level

Even with an overarching functional dysconnectivity model of adolescent‐onset schizophrenia (AOS), there have been no functional connectome (FC) biomarkers identified for predicting patients' specific symptom domains. Adolescence is a period of dramatic brain maturation, with substantial interi...