Eukaryotic translation initiation factor eIF4G2 opens novel paths for protein synthesis in development, apoptosis and cell differentiation

• Published in: Cell proliferation Vol. 56; no. 3; pp. e13367 - n/a
• Main Authors: Liu, Yudi, Cui, Jiuwei, Hoffman, Andrew R., Hu, Ji‐Fan
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.03.2023; John Wiley and Sons Inc
• Subjects: Apoptosis; Binding sites; Cell Differentiation; Cell survival; Cloning; Cyclin-dependent kinases; Differentiation (biology); Embryogenesis; Embryonic development; Embryonic growth stage; Eukaryotic Initiation Factor-4E - genetics; Eukaryotic Initiation Factor-4E - metabolism; Eukaryotic Initiation Factor-4G - genetics; Eukaryotic Initiation Factor-4G - metabolism; Gene expression; Genetic translation; Humans; Initiation factor eIF-4E; Initiation factor eIF-4G; Initiation factors; Kinases; Physiological aspects; Physiological effects; Protein binding; Protein Biosynthesis; Protein Processing, Post-Translational; Protein synthesis; Proteins; Recruitment; Review; Reviews

Protein translation is a critical regulatory event involved in nearly all physiological and pathological processes. Eukaryotic translation initiation factors are dedicated to translation initiation, the most highly regulated stage of protein synthesis. Eukaryotic translation initiation factor 4G2 (e...