Mitochondrial Functions in Infection and Immunity

• Published in: Trends in cell biology Vol. 30; no. 4; pp. 263 - 275
• Main Authors: Tiku, Varnesh, Tan, Man-Wah, Dikic, Ivan
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.04.2020; Elsevier BV; The Authors. Published by Elsevier Ltd
• Subjects: bacteria; Bacterial diseases; cell death; Homeostasis; Immune response; Immunity; Infections; innate immunity; Microorganisms; Mitochondria; mitochondrial metabolism; mitochondrial morphology; Pathogenesis; Review; viruses; viruses; bacteria; cell death; innate immunity; mitochondrial morphology; mitochondrial metabolism

Mitochondria have a central role in regulating a range of cellular activities and host responses upon bacterial infection. Multiple pathogens affect mitochondria dynamics and functions to influence their intracellular survival or evade host immunity. On the other side, major host responses elicited...