A Stretchable Electrochemical Sensor for Inducing and Monitoring Cell Mechanotransduction in Real Time

• Published in: Angewandte Chemie International Edition Vol. 56; no. 32; pp. 9454 - 9458
• Main Authors: Liu, Yan‐Ling, Qin, Yu, Jin, Zi‐He, Hu, Xue‐Bo, Chen, Miao‐Miao, Liu, Rong, Amatore, Christian, Huang, Wei‐Hua
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.08.2017; Wiley-VCH Verlag
• Edition: International ed. in English
• Subjects: Analytical chemistry; Biosensing Techniques; biosensors; Carbon nanotubes; cell mechanotransduction; Cells, Cultured; Chemical Sciences; electrochemical detection; Electrochemical Techniques; Electrochemistry; Epithelial cells; Gold; Gold - chemistry; hierarchical networks; Human Umbilical Vein Endothelial Cells - chemistry; Human Umbilical Vein Endothelial Cells - metabolism; Humans; Mechanotransduction; Mechanotransduction, Cellular; Metal Nanoparticles - chemistry; Monitoring; Nanotechnology; Nanotubes; Nanotubes, Carbon - chemistry; Nitric Oxide - biosynthesis; Nitric Oxide - chemistry; Nitric Oxide Synthase Type III - metabolism; Particle Size; Real time; Sensors; stretchable sensors; Stretching; Time Factors; stretchable sensors; electrochemical detection; hierarchical networks; biosensors; cell mechanotransduction

Existing methods offer little direct and real‐time information about stretch‐triggered biochemical responses during cell mechanotransduction. A novel stretchable electrochemical sensor is reported that takes advantage of a hierarchical percolation network of carbon nanotubes and gold nanotubes (CNT‐...