Accurate prediction of individual subject identity and task, but not autism diagnosis, from functional connectomes

• Published in: Human brain mapping Vol. 41; no. 9; pp. 2249 - 2262
• Main Authors: Byrge, Lisa, Kennedy, Daniel P.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 15.06.2020
• Subjects: Adult; Autism; Autism Spectrum Disorder - diagnostic imaging; Autism Spectrum Disorder - physiopathology; Biomarkers; Brain - diagnostic imaging; Brain - physiology; Connectome; Diagnosis; fcMRI; Female; functional connectivity; Functional magnetic resonance imaging; Humans; individual differences; Individuality; Magnetic Resonance Imaging; Male; Middle Aged; naturalistic viewing; Nerve Net - diagnostic imaging; Nerve Net - physiology; Rest; resting state; Social aspects; Social Perception; Visual Perception - physiology; naturalistic viewing; resting state; functional connectivity; fcMRI; autism; individual differences

Despite enthusiasm about the potential for using fMRI‐based functional connectomes in the development of biomarkers for autism spectrum disorder (ASD), the literature is full of negative findings—failures to distinguish ASD functional connectomes from those of typically developing controls (TD)—and...