Plasma calprotectin as a biomarker of ultrasound synovitis in rheumatoid arthritis patients receiving IL-6 antagonists or JAK inhibitors

• Published in: Therapeutic advances in musculoskeletal disease Vol. 14; p. 1759720X221114105
• Main Authors: Frade-Sosa, Beatriz, Ponce, Andrés, Inciarte-Mundo, José, Morlà, Rosa, Ruiz-Esquide, Viginia, Macías, Laura, Azuaga, Ana Belen, Ramirez, Julio, Cañete, Juan D., Yague, Jordi, Auge, Josep M., Gomez-Puerta, José A., Sanmarti, Raimon
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 2022; SAGE PUBLICATIONS, INC; SAGE Publishing
• Subjects: Biomarkers; Monoclonal antibodies; Musculoskeletal diseases; Original Research; Plasma; Rheumatoid arthritis; Ultrasonic imaging; acute phase proteins; leukocyte L1 antigen complex (calprotectin); ultrasonography; rheumatoid arthritis; biomarkers

Objectives: To analyse the accuracy of plasma calprotectin in patients with rheumatoid arthritis (RA) receiving monoclonal antibodies against IL-6 receptors (anti-rIL-6) or JAK inhibitors (JAKis) in detecting ultrasound (US) synovitis and compare it with acute phase reactants [high-sensitivity C-rea...