Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade therapy - Wang, Xiaodong; Yang, Xiaohui; Zhang, Chang; Wang, Yang; Cheng, Tianyou; Duan, Liqiang; Tong, Zhou; Tan, Shuguang; Zhang, Hangjie; Saw, Phei Er; Gu, Yinmin; Wang, Jinhua; et al. (Proceedings of the National Academy of Sciences - PNAS, 2020)
Keywords: AKT protein; Antibodies; Anticancer properties; Antitumor activity; Apoptosis; Biological Sciences; Biomarkers; Blocking antibodies; Cell death; Cell growth; Cell proliferation; Colonies; Immune checkpoint; Immune system; Ligands; Lymphocytes; Lymphocytes T; PD-1 protein; PD-L1 protein; Tumor cells; Tumor suppressor genes; Tumors; Xenografts; Xenotransplantation; tumor cell-intrinsic PD-L1; tumor suppressor; drug resistance; biomarker; tumor cell-intrinsic PD-1