Tumor immunotherapy based on tumor-derived heat shock proteins (Review)

• Published in: Oncology letters Vol. 6; no. 6; pp. 1543 - 1549
• Main Authors: ZHANG, YUNFEI, ZHENG, LIANHE
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01.12.2013; Spandidos Publications UK Ltd
• Subjects: 20th century; Animals; Antigens; Clinical trials; Heat shock proteins; Immune system; Immunotherapy; Metastasis; molecular chaperone; Oncology; Peptides; Studies; Tumors; vaccine; Vaccines; molecular chaperone; vaccine; heat shock proteins; immunotherapy

Heat shock proteins (HSPs), the most important type of molecular chaperone, are expressed in all eukaryotic cells and have multiple functions, including the folding and unfolding of other proteins and peptides, the transport of proteins and peptides and the support of antigen presentation processes....