High-amplitude cofluctuations in cortical activity drive functional connectivity

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 117; no. 45; pp. 28393 - 28401
• Main Authors: Esfahlani, Farnaz Zamani, Jo, Youngheun, Faskowitz, Joshua, Byrge, Lisa, Kennedy, Daniel P., Sporns, Olaf, Betzel, Richard F.
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 10.11.2020
• Subjects: Activity patterns; Amplitudes; Biological Sciences; Biomarkers; Brain; Brain - diagnostic imaging; Brain - physiology; Brain architecture; Brain Mapping - methods; Cognition; Fluctuations; Frames; Humans; Magnetic Resonance Imaging - methods; Modular structures; Nerve Net - physiology; Nervous system; Neural networks; Neural Pathways; Oxygen - blood; Physical Sciences; Rest - physiology; Time dependence; naturalistic stimuli; time-varying connectivity; dynamics; functional connectivity

Resting-state functional connectivity is used throughout neuroscience to study brain organization and to generate biomarkers of development, disease, and cognition. The processes that give rise to correlated activity are, however, poorly understood. Here we decompose resting-state functional connect...