Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis - Zhou, Xiaopu; Chen, Yu; Mok, Kin Y.; Zhao, Qianhua; Chen, Keliang; Chen, Yuewen; Hardy, John; Li, Yun; Fu, Amy K. Y.; Guo, Qihao; Ip, Nancy Y. (Proceedings of the National Academy of Sciences - PNAS, 2018)
Keywords: Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease - genetics; Alzheimer Disease - immunology; Alzheimer Disease - pathology; Alzheimer's disease; Apolipoprotein E; Apolipoproteins E - genetics; Asian People - genetics; Biological Sciences; Biomarkers; Blood; China; Cohort Studies; Female; Gene expression; Gene sequencing; Genetic Predisposition to Disease; Genetics; Genome-Wide Association Study; Genomes; Genotype; Genotypes; Geriatrics; Humans; Immune system; Immune System - immunology; Loci; Male; Middle Aged; Network analysis; Neurodegenerative diseases; Older people; Pathogenesis; Phenotypes; Potassium Channels, Inwardly Rectifying - genetics; Potassium Channels, Inwardly Rectifying - immunology; Risk; Risk analysis; Risk Factors; Transcription; China; GWAS; immune; Alzheimer’s disease; whole-genome sequencing; risk variant