Expanded Polyglutamine-containing N-terminal Huntingtin Fragments Are Entirely Degraded by Mammalian Proteasomes - Juenemann, Katrin; Schipper-Krom, Sabine; Wiemhoefer, Anne; Kloss, Alexander; Sanz Sanz, Alicia; Reits, Eric A.J. (The Journal of biological chemistry, 2013)
Keywords: Aggregation; Animals; Autophagy; Cell Line; Humans; Huntingtin Protein; Huntington Disease; Mice; Mice, Knockout; Molecular Bases of Disease; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Peptides - genetics; Peptides - metabolism; Polyglutamine; Proteasome; Proteasome Endopeptidase Complex - genetics; Proteasome Endopeptidase Complex - metabolism; Proteolysis; Repetitive Sequences, Amino Acid; Aggregation; Huntington Disease; Polyglutamine; Autophagy; Proteasome