Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation
MFAP4 (microfibrillar-associated protein 4) is an extracellular glycoprotein found in elastic fibers without a clearly defined role in elastic fiber assembly. In the present study, we characterized molecular interactions between MFAP4 and elastic fiber components. We established that MFAP4 primarily...
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Published in | The Journal of biological chemistry Vol. 291; no. 3; pp. 1103 - 1114 |
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Main Authors | , , , , , , , , , , , |
Format | Journal Article |
Language | English |
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Elsevier Inc
15.01.2016
American Society for Biochemistry and Molecular Biology |
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Abstract | MFAP4 (microfibrillar-associated protein 4) is an extracellular glycoprotein found in elastic fibers without a clearly defined role in elastic fiber assembly. In the present study, we characterized molecular interactions between MFAP4 and elastic fiber components. We established that MFAP4 primarily assembles into trimeric and hexameric structures of homodimers. Binding analysis revealed that MFAP4 specifically binds tropoelastin and fibrillin-1 and -2, as well as the elastin cross-linking amino acid desmosine, and that it co-localizes with fibrillin-1-positive fibers in vivo. Site-directed mutagenesis disclosed residues Phe241 and Ser203 in MFAP4 as being crucial for type I collagen, elastin, and tropoelastin binding. Furthermore, we found that MFAP4 actively promotes tropoelastin self-assembly. In conclusion, our data identify MFAP4 as a new ligand of microfibrils and tropoelastin involved in proper elastic fiber organization. |
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AbstractList | MFAP4 (microfibrillar-associated protein 4) is an extracellular glycoprotein found in elastic fibers without a clearly defined role in elastic fiber assembly. In the present study, we characterized molecular interactions between MFAP4 and elastic fiber components. We established that MFAP4 primarily assembles into trimeric and hexameric structures of homodimers. Binding analysis revealed that MFAP4 specifically binds tropoelastin and fibrillin-1 and -2, as well as the elastin cross-linking amino acid desmosine, and that it co-localizes with fibrillin-1-positive fibers in vivo. Site-directed mutagenesis disclosed residues Phe(241) and Ser(203) in MFAP4 as being crucial for type I collagen, elastin, and tropoelastin binding. Furthermore, we found that MFAP4 actively promotes tropoelastin self-assembly. In conclusion, our data identify MFAP4 as a new ligand of microfibrils and tropoelastin involved in proper elastic fiber organization. MFAP4 (microfibrillar-associated protein 4) is an extracellular glycoprotein found in elastic fibers without a clearly defined role in elastic fiber assembly. In the present study, we characterized molecular interactions between MFAP4 and elastic fiber components. We established that MFAP4 primarily assembles into trimeric and hexameric structures of homodimers. Binding analysis revealed that MFAP4 specifically binds tropoelastin and fibrillin-1 and -2, as well as the elastin cross-linking amino acid desmosine, and that it co-localizes with fibrillin-1-positive fibers in vivo . Site-directed mutagenesis disclosed residues Phe 241 and Ser 203 in MFAP4 as being crucial for type I collagen, elastin, and tropoelastin binding. Furthermore, we found that MFAP4 actively promotes tropoelastin self-assembly. In conclusion, our data identify MFAP4 as a new ligand of microfibrils and tropoelastin involved in proper elastic fiber organization. MFAP4 (microfibrillar-associated protein 4) is an extracellular glycoprotein found in elastic fibers without a clearly defined role in elastic fiber assembly. In the present study, we characterized molecular interactions between MFAP4 and elastic fiber components. We established that MFAP4 primarily assembles into trimeric and hexameric structures of homodimers. Binding analysis revealed that MFAP4 specifically binds tropoelastin and fibrillin-1 and -2, as well as the elastin cross-linking amino acid desmosine, and that it co-localizes with fibrillin-1-positive fibers in vivo. Site-directed mutagenesis disclosed residues Phe241 and Ser203 in MFAP4 as being crucial for type I collagen, elastin, and tropoelastin binding. Furthermore, we found that MFAP4 actively promotes tropoelastin self-assembly. In conclusion, our data identify MFAP4 as a new ligand of microfibrils and tropoelastin involved in proper elastic fiber organization. |
Author | Wohl, Alexander P. Sorensen, Grith L. Pilecki, Bartosz Schlosser, Anders Sengle, Gerhard Zuk, Alexandra V. Heumüller, Stefanie E. Holmskov, Uffe Moestrup, Soren K. Holm, Anne T. Moeller, Jesper B. Wallis, Russell |
Author_xml | – sequence: 1 givenname: Bartosz surname: Pilecki fullname: Pilecki, Bartosz organization: From the Department of Cancer and Inflammation Research, Institute of Molecular Medicine, Faculty of Health Sciences, University of Southern Denmark, 5000 Odense C, Denmark – sequence: 2 givenname: Anne T. surname: Holm fullname: Holm, Anne T. organization: From the Department of Cancer and Inflammation Research, Institute of Molecular Medicine, Faculty of Health Sciences, University of Southern Denmark, 5000 Odense C, Denmark – sequence: 3 givenname: Anders surname: Schlosser fullname: Schlosser, Anders organization: From the Department of Cancer and Inflammation Research, Institute of Molecular Medicine, Faculty of Health Sciences, University of Southern Denmark, 5000 Odense C, Denmark – sequence: 4 givenname: Jesper B. surname: Moeller fullname: Moeller, Jesper B. organization: From the Department of Cancer and Inflammation Research, Institute of Molecular Medicine, Faculty of Health Sciences, University of Southern Denmark, 5000 Odense C, Denmark – sequence: 5 givenname: Alexander P. surname: Wohl fullname: Wohl, Alexander P. organization: the Center for Biochemistry, Faculty of Medicine and – sequence: 6 givenname: Alexandra V. surname: Zuk fullname: Zuk, Alexandra V. organization: the Center for Biochemistry, Faculty of Medicine and – sequence: 7 givenname: Stefanie E. surname: Heumüller fullname: Heumüller, Stefanie E. organization: the Center for Biochemistry, Faculty of Medicine and – sequence: 8 givenname: Russell surname: Wallis fullname: Wallis, Russell organization: the Department of Infection, Immunity and Inflammation, and Department of Molecular and Cell Biology, University of Leicester, Leicester LE1 9HN, United Kingdom, and – sequence: 9 givenname: Soren K. surname: Moestrup fullname: Moestrup, Soren K. organization: From the Department of Cancer and Inflammation Research, Institute of Molecular Medicine, Faculty of Health Sciences, University of Southern Denmark, 5000 Odense C, Denmark – sequence: 10 givenname: Gerhard surname: Sengle fullname: Sengle, Gerhard organization: the Center for Biochemistry, Faculty of Medicine and – sequence: 11 givenname: Uffe surname: Holmskov fullname: Holmskov, Uffe organization: From the Department of Cancer and Inflammation Research, Institute of Molecular Medicine, Faculty of Health Sciences, University of Southern Denmark, 5000 Odense C, Denmark – sequence: 12 givenname: Grith L. surname: Sorensen fullname: Sorensen, Grith L. email: glsorensen@health.sdu.dk organization: From the Department of Cancer and Inflammation Research, Institute of Molecular Medicine, Faculty of Health Sciences, University of Southern Denmark, 5000 Odense C, Denmark |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26601954$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1038/nmeth.2089 10.1016/j.molimm.2010.09.019 10.1111/j.1365-3083.2006.01778.x 10.1074/jbc.M608204200 10.1021/bi050530d 10.1152/ajplung.00351.2014 10.1017/erm.2013.9 10.1183/09031936.00064611 10.1042/bj3250391 10.1136/thoraxjnl-2014-206609 10.1038/ng1297 10.1074/jbc.M609692200 10.1038/srep00164 10.1074/jbc.M400212200 10.1016/S0006-3495(00)76713-0 10.1074/jbc.M113.520577 10.1083/jcb.129.4.1165 10.1074/jbc.M109.019364 10.1073/pnas.201523798 10.1074/jbc.M608627200 10.1136/thoraxjnl-2014-205091 10.1172/JCI4487 10.1074/jbc.M604131200 10.1006/jmbi.1996.0237 10.1074/jbc.M707820200 10.1016/j.cis.2010.10.003 10.1093/bioinformatics/bti770 10.1002/elps.1150181505 10.1161/CIRCULATIONAHA.108.843516 10.1016/j.rmed.2014.06.003 10.1074/jbc.M110.130021 10.1093/nar/gkg520 10.4049/jimmunol.179.1.455 10.1136/jmg.2005.039669 10.1074/jbc.M109.061523 10.4049/jimmunol.0901526 10.1042/BJ20061145 10.1074/jbc.274.45.32234 10.1046/j.1432-1327.1999.00891.x 10.1073/pnas.0908268106 10.1016/j.yexcr.2005.03.005 10.1083/jcb.200611026 10.1016/S0021-9258(18)82207-4 10.1371/journal.pone.0082383 10.1074/jbc.274.42.30196 10.1161/01.CIR.0000038109.84500.1E 10.1016/S0021-9258(18)71514-7 10.1371/journal.pone.0082243 10.1046/j.1432-1327.1998.2580001.x 10.1016/S0968-0004(00)88963-X 10.1093/nar/gkn750 10.1177/002215549904700809 10.1074/jbc.M209201200 10.1002/bdrc.20111 10.1038/sj.emboj.7601500 10.1007/s00441-009-0822-x 10.1074/jbc.M506832200 10.1016/j.jchromb.2011.05.011 10.1002/pro.2177 10.1074/jbc.M511599200 10.1042/bj1730857 10.1002/bip.10512 10.1038/415168a 10.1038/415171a |
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Keywords | site-directed mutagenesis analytical ultracentrifugation calcium-binding protein microfibrillar-associated protein 4 surface plasmon resonance (SPR) elastin fibrillin |
Language | English |
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References | Yeo, Keeley, Weiss (bib4) 2011; 167 Carta, Pereira, Arteaga-Solis, Lee-Arteaga, Lenart, Starcher, Merkel, Sukoyan, Kerkis, Hazeki, Keene, Sakai, Ramirez (bib13) 2006; 281 Pilecki, Schlosser, Wulf-Johansson, Trian, Moeller, Marcussen, Aguilar-Pimentel, de Angelis, Vestbo, Berger, Holmskov, Sorensen (bib64) 2015; 70 Schlosser, Thomsen, Shipley, Hein, Brasch, Tornøe, Nielsen, Skjødt, Palaniyar, Steinhilber, McCormack, Holmskov (bib25) 2006; 64 Procopio, Pelavin, Lee, Yeilding (bib16) 1999; 274 Arnold, Bordoli, Kopp, Schwede (bib27) 2006; 22 Holm, Wulf-Johansson, Hvidsten, Jorgensen, Schlosser, Pilecki, Ormhøj, Moeller, Johannsen, Baun, Andersen, Schneider, Hegermann, Ochs, Götz, Schulz, de Angelis, Vestbo, Holmskov, Sorensen (bib65) 2015; 308 Thomsen, Schlosser, Holmskov, Sorensen (bib15) 2011; 48 Shrive, Moeller, Burns, Paterson, Shaw, Schlosser, Sorensen, Greenhough, Holmskov (bib17) 2014; 289 Vrhovski, Weiss (bib3) 1998; 258 Schlosser, Thomsen, Moeller, Nielsen, Tornøe, Mollenhauer, Moestrup, Holmskov (bib14) 2009; 183 Lausen, Lynch, Schlosser, Tornoe, Saekmose, Teisner, Willis, Crouch, Schwaeble, Holmskov (bib20) 1999; 274 Lindberg, Engström, de Verdier, Nihlén, Anderson, Forsman-Semb, Svartengren (bib51) 2012; 39 Kairies, Beisel, Fuentes-Prior, Tsuda, Muta, Iwanaga, Bode, Huber, Kawabata (bib18) 2001; 98 Tanio, Kondo, Sugio, Kohno (bib43) 2007; 282 Robinson, Arteaga-Solis, Baldock, Collod-Béroud, Booms, De Paepe, Dietz, Guo, Handford, Judge, Kielty, Loeys, Milewicz, Ney, Ramirez, Reinhardt, Tiedemann, Whiteman, Godfrey (bib45) 2006; 43 Liu, Zhao, Gao, Pawlyk, Starcher, Spencer, Yanagisawa, Zuo, Li (bib54) 2004; 36 Guex, Peitsch (bib30) 1997; 18 Laue, Bhairavi, Ridgeway, Pelletier (bib33) 1992 Charbonneau, Dzamba, Ono, Keene, Corson, Reinhardt, Sakai (bib41) 2003; 278 Wu, Weiss (bib60) 1999; 266 Johansson, Roberts, Schlosser, Andersen, Carlsen, Wulf-Johansson, Saekmose, Titlestad, Tornoe, Miller, Tal-Singer, Holmskov, Vestbo, Sorensen (bib52) 2014; 108 Schwede, Kopp, Guex, Peitsch (bib29) 2003; 31 Rock, Cain, Freeman, Morgan, Mellody, Marson, Shuttleworth, Weiss, Kielty (bib7) 2004; 279 Ma, Turino, Lin (bib50) 2011; 879 Thomassin, Werneck, Broekelmann, Gleyzal, Hornstra, Mecham, Sommer (bib53) 2005; 280 Narayanan, Page, Kuzan, Cooper (bib58) 1978; 173 Wulf-Johansson, Lock Johansson, Schlosser, Trommelholt Holm, Rasmussen, Mickley, Diederichsen, Munkholm, Poulsen, Tornøe, Nielsen, Marcussen, Vestbo, Saekmose, Holmskov, Sorensen (bib23) 2013; 8 Saekmose, Schlosser, Holst, Johansson, Wulf-Johansson, Tornøe, Vestbo, Kyvik, Barington, Holmskov, Sørensen (bib32) 2013; 8 Schneider, Rasband, Eliceiri (bib42) 2012; 9 Baldwin, Simpson, Steer, Cain, Kielty (bib2) 2013; 15 Ramirez, Sakai (bib6) 2010; 339 Choudhury, McGovern, Ridley, Cain, Baldwin, Wang, Guo, Mironov, Drymoussi, Trump, Shuttleworth, Baldock, Kielty (bib8) 2009; 284 Kobayashi, Tashima, Masuda, Shozawa, Numata, Miyauchi, Hayakawa (bib22) 1989; 264 Reinhardt, Keene, Corson, Pöschl, Bächinger, Gambee, Sakai (bib37) 1996; 258 Koch, Veit, Stricker, Bhatt, Kutsch, Zhou, Reinders, Hahn, Song, Burgeson, Gerecke, Mundlos, Gordon (bib39) 2006; 281 Thomsen, Moeller, Schlosser, Sorensen, Moestrup, Palaniyar, Wallis, Mollenhauer, Holmskov (bib49) 2010; 285 Nakamura, Lozano, Ikeda, Iwanaga, Hinek, Minamisawa, Cheng, Kobuke, Dalton, Takada, Tashiro, Ross, Honjo, Chien (bib61) 2002; 415 Schuck (bib35) 2000; 78 Li, Faury, Taylor, Davis, Boyle, Mecham, Stenzel, Boak, Keating (bib11) 1998; 102 Kiefer, Arnold, Künzli, Bordoli, Schwede (bib28) 2009; 37 Bedell-Hogan, Trackman, Abrams, Rosenbloom, Kagan (bib5) 1993; 268 Toyoshima, Nishi, Kusama, Kobayashi, Itano (bib21) 2005; 307 Toyoshima, Yamashita, Furuichi, Shishibori, Itano, Kobayashi (bib24) 1999; 47 Garlatti, Belloy, Martin, Lacroix, Matsushita, Endo, Fujita, Fontecilla-Camps, Arlaud, Thielens, Gaboriaud (bib19) 2007; 26 Wachi, Sato, Nakazawa, Nonaka, Szabo, Urban, Yasunaga, Maeda, Okamoto, Starcher, Li, Mecham, Seyama (bib59) 2007; 402 Girija, Dodds, Roscher, Reid, Wallis (bib36) 2007; 179 Kasamatsu, Hachiya, Fujimura, Sriwiriyanont, Haketa, Visscher, Kitzmiller, Bello, Kitahara, Kobinger, Takema (bib26) 2011; 1 Lemaire, Bayle, Mecham, Lafyatis (bib9) 2007; 282 Bellingham, Lillie, Gosline, Wright, Starcher, Bailey, Woodhouse, Keeley (bib57) 2003; 70 El-Hallous, Sasaki, Hubmacher, Getie, Tiedemann, Brinckmann, Bätge, Davis, Reinhardt (bib47) 2007; 282 Hirai, Ohbayashi, Horiguchi, Okawa, Hagiwara, Chien, Kita, Nakamura (bib55) 2007; 176 Wallis, Drickamer (bib34) 1997; 325 Peitsch, Wells, Stampf, Sussman (bib31) 1995; 20 Wagenseil, Mecham (bib1) 2007; 81 Sengle, Charbonneau, Ono, Sasaki, Alvarez, Keene, Bächinger, Sakai (bib38) 2008; 283 Doolittle, McNamara, Lin (bib48) 2012; 21 Mäki, Räsänen, Tikkanen, Sormunen, Mäkikallio, Kivirikko, Soininen (bib12) 2002; 106 Charbonneau, Carlson, Tufa, Sengle, Manalo, Carlberg, Ramirez, Keene, Sakai (bib40) 2010; 285 Zhang, Hu, Ramirez (bib44) 1995; 129 Yanagisawa, Davis, Starcher, Ouchi, Yanagisawa, Richardson, Olson (bib62) 2002; 415 Horiguchi, Inoue, Ohbayashi, Hirai, Noda, Marmorstein, Yabe, Takagi, Akama, Kita, Kimura, Nakamura (bib10) 2009; 106 Pilop, Aregger, Gorman, Brunisholz, Gerrits, Schaffner, Gorman, Matyas, Carrel, Frey (bib46) 2009; 120 Brandsma, van den Berge, Postma, Jonker, Brouwer, Paré, Sin, Bossé, Laviolette, Karjalainen, Fehrmann, Nickle, Hao, Spanjer, Timens, Franke (bib63) 2015; 70 Clarke, Wise, Cain, Kielty, Weiss (bib56) 2005; 44 Kiefer (10.1074/jbc.M115.681775_bib28) 2009; 37 Laue (10.1074/jbc.M115.681775_bib33) 1992 Lausen (10.1074/jbc.M115.681775_bib20) 1999; 274 Pilop (10.1074/jbc.M115.681775_bib46) 2009; 120 Thomsen (10.1074/jbc.M115.681775_bib49) 2010; 285 Arnold (10.1074/jbc.M115.681775_bib27) 2006; 22 Choudhury (10.1074/jbc.M115.681775_bib8) 2009; 284 Kairies (10.1074/jbc.M115.681775_bib18) 2001; 98 Liu (10.1074/jbc.M115.681775_bib54) 2004; 36 Reinhardt (10.1074/jbc.M115.681775_bib37) 1996; 258 Girija (10.1074/jbc.M115.681775_bib36) 2007; 179 Lindberg (10.1074/jbc.M115.681775_bib51) 2012; 39 Schlosser (10.1074/jbc.M115.681775_bib25) 2006; 64 Pilecki (10.1074/jbc.M115.681775_bib64) 2015; 70 Horiguchi (10.1074/jbc.M115.681775_bib10) 2009; 106 Tanio (10.1074/jbc.M115.681775_bib43) 2007; 282 Johansson (10.1074/jbc.M115.681775_bib52) 2014; 108 Procopio (10.1074/jbc.M115.681775_bib16) 1999; 274 Nakamura (10.1074/jbc.M115.681775_bib61) 2002; 415 Narayanan (10.1074/jbc.M115.681775_bib58) 1978; 173 Garlatti (10.1074/jbc.M115.681775_bib19) 2007; 26 Zhang (10.1074/jbc.M115.681775_bib44) 1995; 129 Toyoshima (10.1074/jbc.M115.681775_bib24) 1999; 47 Schwede (10.1074/jbc.M115.681775_bib29) 2003; 31 Wallis (10.1074/jbc.M115.681775_bib34) 1997; 325 Holm (10.1074/jbc.M115.681775_bib65) 2015; 308 Mäki (10.1074/jbc.M115.681775_bib12) 2002; 106 Wu (10.1074/jbc.M115.681775_bib60) 1999; 266 Schuck (10.1074/jbc.M115.681775_bib35) 2000; 78 Hirai (10.1074/jbc.M115.681775_bib55) 2007; 176 Wagenseil (10.1074/jbc.M115.681775_bib1) 2007; 81 Yeo (10.1074/jbc.M115.681775_bib4) 2011; 167 Carta (10.1074/jbc.M115.681775_bib13) 2006; 281 Bellingham (10.1074/jbc.M115.681775_bib57) 2003; 70 Guex (10.1074/jbc.M115.681775_bib30) 1997; 18 Wachi (10.1074/jbc.M115.681775_bib59) 2007; 402 Charbonneau (10.1074/jbc.M115.681775_bib40) 2010; 285 Thomassin (10.1074/jbc.M115.681775_bib53) 2005; 280 Schlosser (10.1074/jbc.M115.681775_bib14) 2009; 183 Yanagisawa (10.1074/jbc.M115.681775_bib62) 2002; 415 Clarke (10.1074/jbc.M115.681775_bib56) 2005; 44 Kasamatsu (10.1074/jbc.M115.681775_bib26) 2011; 1 Robinson (10.1074/jbc.M115.681775_bib45) 2006; 43 Bedell-Hogan (10.1074/jbc.M115.681775_bib5) 1993; 268 Rock (10.1074/jbc.M115.681775_bib7) 2004; 279 Thomsen (10.1074/jbc.M115.681775_bib15) 2011; 48 El-Hallous (10.1074/jbc.M115.681775_bib47) 2007; 282 Brandsma (10.1074/jbc.M115.681775_bib63) 2015; 70 Vrhovski (10.1074/jbc.M115.681775_bib3) 1998; 258 Li (10.1074/jbc.M115.681775_bib11) 1998; 102 Kobayashi (10.1074/jbc.M115.681775_bib22) 1989; 264 Koch (10.1074/jbc.M115.681775_bib39) 2006; 281 Lemaire (10.1074/jbc.M115.681775_bib9) 2007; 282 Doolittle (10.1074/jbc.M115.681775_bib48) 2012; 21 Wulf-Johansson (10.1074/jbc.M115.681775_bib23) 2013; 8 Saekmose (10.1074/jbc.M115.681775_bib32) 2013; 8 Peitsch (10.1074/jbc.M115.681775_bib31) 1995; 20 Toyoshima (10.1074/jbc.M115.681775_bib21) 2005; 307 Baldwin (10.1074/jbc.M115.681775_bib2) 2013; 15 Sengle (10.1074/jbc.M115.681775_bib38) 2008; 283 Schneider (10.1074/jbc.M115.681775_bib42) 2012; 9 Ramirez (10.1074/jbc.M115.681775_bib6) 2010; 339 Ma (10.1074/jbc.M115.681775_bib50) 2011; 879 Shrive (10.1074/jbc.M115.681775_bib17) 2014; 289 Charbonneau (10.1074/jbc.M115.681775_bib41) 2003; 278 |
References_xml | – volume: 70 start-page: 445 year: 2003 end-page: 455 ident: bib57 article-title: Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties publication-title: Biopolymers contributor: fullname: Keeley – volume: 108 start-page: 1336 year: 2014 end-page: 1344 ident: bib52 article-title: Microfibrillar-associated protein 4: a potential biomarker of chronic obstructive pulmonary disease publication-title: Respir. Med contributor: fullname: Sorensen – volume: 20 start-page: 82 year: 1995 end-page: 84 ident: bib31 article-title: The Swiss-3DImage collection and PDB-Browser on the World-Wide Web publication-title: Trends Biochem. Sci contributor: fullname: Sussman – volume: 129 start-page: 1165 year: 1995 end-page: 1176 ident: bib44 article-title: Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils publication-title: J. Cell Biol contributor: fullname: Ramirez – volume: 15 start-page: e8 year: 2013 ident: bib2 article-title: Elastic fibres in health and disease publication-title: Expert Rev. Mol. Med contributor: fullname: Kielty – volume: 21 start-page: 1808 year: 2012 end-page: 1823 ident: bib48 article-title: Correlating structure and function during the evolution of fibrinogen-related domains publication-title: Protein Sci contributor: fullname: Lin – volume: 339 start-page: 71 year: 2010 end-page: 82 ident: bib6 article-title: Biogenesis and function of fibrillin assemblies publication-title: Cell Tissue Res contributor: fullname: Sakai – volume: 48 start-page: 369 year: 2011 end-page: 381 ident: bib15 article-title: Ficolins and FIBCD1: soluble and membrane bound pattern recognition molecules with acetyl group selectivity publication-title: Mol. Immunol contributor: fullname: Sorensen – volume: 98 start-page: 13519 year: 2001 end-page: 13524 ident: bib18 article-title: The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems publication-title: Proc. Natl. Acad. Sci. U.S.A contributor: fullname: Kawabata – volume: 81 start-page: 229 year: 2007 end-page: 240 ident: bib1 article-title: New insights into elastic fiber assembly publication-title: Birth Defects Res. C. Embryo Today contributor: fullname: Mecham – volume: 284 start-page: 24553 year: 2009 end-page: 24567 ident: bib8 article-title: Differential regulation of elastic fiber formation by fibulin-4 and -5 publication-title: J. Biol. Chem contributor: fullname: Kielty – volume: 282 start-page: 3889 year: 2007 end-page: 3895 ident: bib43 article-title: Trivalent recognition unit of innate immunity system: crystal structure of trimeric human M-ficolin fibrinogen-like domain publication-title: J. Biol. Chem contributor: fullname: Kohno – volume: 402 start-page: 63 year: 2007 end-page: 70 ident: bib59 article-title: Domains 16 and 17 of tropoelastin in elastic fibre formation publication-title: Biochem. J contributor: fullname: Seyama – volume: 258 start-page: 1 year: 1998 end-page: 18 ident: bib3 article-title: Biochemistry of tropoelastin publication-title: Eur. J. Biochem contributor: fullname: Weiss – volume: 279 start-page: 23748 year: 2004 end-page: 23758 ident: bib7 article-title: Molecular basis of elastic fiber formation: critical interactions and a tropoelastin-fibrillin-1 cross-link publication-title: J. Biol. Chem contributor: fullname: Kielty – volume: 274 start-page: 32234 year: 1999 end-page: 32240 ident: bib20 article-title: Microfibril-associated protein 4 is present in lung washings and binds to the collagen region of lung surfactant protein D publication-title: J. Biol. Chem contributor: fullname: Holmskov – volume: 268 start-page: 10345 year: 1993 end-page: 10350 ident: bib5 article-title: Oxidation, cross-linking, and insolubilization of recombinant tropoelastin by purified lysyl oxidase publication-title: J. Biol. Chem contributor: fullname: Kagan – volume: 281 start-page: 21546 year: 2006 end-page: 21557 ident: bib39 article-title: Expression of type XXIII collagen mRNA and protein publication-title: J. Biol. Chem contributor: fullname: Gordon – volume: 9 start-page: 671 year: 2012 end-page: 675 ident: bib42 article-title: NIH Image to ImageJ: 25 years of image analysis publication-title: Nat. Methods contributor: fullname: Eliceiri – volume: 106 start-page: 19029 year: 2009 end-page: 19034 ident: bib10 article-title: Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase publication-title: Proc. Natl. Acad. Sci. U.S.A contributor: fullname: Nakamura – volume: 44 start-page: 10271 year: 2005 end-page: 10281 ident: bib56 article-title: Coacervation is promoted by molecular interactions between the PF2 segment of fibrillin-1 and the domain 4 region of tropoelastin publication-title: Biochemistry contributor: fullname: Weiss – volume: 31 start-page: 3381 year: 2003 end-page: 3385 ident: bib29 article-title: SWISS-MODEL: an automated protein homology-modeling server publication-title: Nucleic Acids Res contributor: fullname: Peitsch – volume: 285 start-page: 24943 year: 2010 end-page: 24955 ident: bib40 article-title: studies of mutant fibrillin-1 microfibrils publication-title: J. Biol. Chem contributor: fullname: Sakai – volume: 39 start-page: 839 year: 2012 end-page: 845 ident: bib51 article-title: Total desmosines in plasma and urine correlate with lung function publication-title: Eur. Respir. J contributor: fullname: Svartengren – volume: 183 start-page: 3800 year: 2009 end-page: 3809 ident: bib14 article-title: Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin publication-title: J. Immunol contributor: fullname: Holmskov – volume: 37 start-page: D387 year: 2009 end-page: D392 ident: bib28 article-title: The SWISS-MODEL Repository and associated resources publication-title: Nucleic Acids Res contributor: fullname: Schwede – volume: 70 start-page: 21 year: 2015 end-page: 32 ident: bib63 article-title: A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD publication-title: Thorax contributor: fullname: Franke – volume: 308 start-page: L1114 year: 2015 end-page: L1124 ident: bib65 article-title: Characterization of spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4 publication-title: Am. J. Physiol. Lung. Cell Mol. Physiol contributor: fullname: Sorensen – volume: 879 start-page: 1893 year: 2011 end-page: 1898 ident: bib50 article-title: Quantitation of desmosine and isodesmosine in urine, plasma, and sputum by LC-MS/MS as biomarkers for elastin degradation publication-title: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci contributor: fullname: Lin – volume: 415 start-page: 171 year: 2002 end-page: 175 ident: bib61 article-title: Fibulin-5/DANCE is essential for elastogenesis publication-title: Nature contributor: fullname: Chien – volume: 120 start-page: 983 year: 2009 end-page: 991 ident: bib46 article-title: Proteomic analysis in aortic media of patients with Marfan syndrome reveals increased activity of calpain 2 in aortic aneurysms publication-title: Circulation contributor: fullname: Frey – volume: 278 start-page: 2740 year: 2003 end-page: 2749 ident: bib41 article-title: Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences publication-title: J. Biol. Chem contributor: fullname: Sakai – volume: 258 start-page: 104 year: 1996 end-page: 116 ident: bib37 article-title: Fibrillin-1: organization in microfibrils and structural properties publication-title: J. Mol. Biol contributor: fullname: Sakai – volume: 280 start-page: 42848 year: 2005 end-page: 42855 ident: bib53 article-title: The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers publication-title: J. Biol. Chem contributor: fullname: Sommer – volume: 26 start-page: 623 year: 2007 end-page: 633 ident: bib19 article-title: Structural insights into the innate immune recognition specificities of L- and H-ficolins publication-title: EMBO J contributor: fullname: Gaboriaud – volume: 8 start-page: e82243 year: 2013 ident: bib23 article-title: Localization of microfibrillar-associated protein 4 (MFAP4) in human tissues: clinical evaluation of serum MFAP4 and its association with various cardiovascular conditions publication-title: PLoS One contributor: fullname: Sorensen – volume: 18 start-page: 2714 year: 1997 end-page: 2723 ident: bib30 article-title: SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling publication-title: Electrophoresis contributor: fullname: Peitsch – year: 1992 ident: bib33 publication-title: Analytical Ultracentrifugation in Biochemistry and Polymers Sciences contributor: fullname: Pelletier – volume: 176 start-page: 1061 year: 2007 end-page: 1071 ident: bib55 article-title: Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage publication-title: J. Cell Biol contributor: fullname: Nakamura – volume: 415 start-page: 168 year: 2002 end-page: 171 ident: bib62 article-title: Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo publication-title: Nature contributor: fullname: Olson – volume: 64 start-page: 104 year: 2006 end-page: 116 ident: bib25 article-title: Microfibril-associated protein 4 binds to surfactant protein A (SP-A) and colocalizes with SP-A in the extracellular matrix of the lung publication-title: Scand. J. Immunol contributor: fullname: Holmskov – volume: 282 start-page: 8935 year: 2007 end-page: 8946 ident: bib47 article-title: Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin publication-title: J. Biol. Chem contributor: fullname: Reinhardt – volume: 264 start-page: 17437 year: 1989 end-page: 17444 ident: bib22 article-title: Isolation and characterization of a new 36-kDa microfibril-associated glycoprotein from porcine aorta publication-title: J. Biol. Chem contributor: fullname: Hayakawa – volume: 282 start-page: 800 year: 2007 end-page: 808 ident: bib9 article-title: Microfibril-associated MAGP-2 stimulates elastic fiber assembly publication-title: J. Biol. Chem contributor: fullname: Lafyatis – volume: 78 start-page: 1606 year: 2000 end-page: 1619 ident: bib35 article-title: Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling publication-title: Biophys. J contributor: fullname: Schuck – volume: 289 start-page: 2880 year: 2014 end-page: 2887 ident: bib17 article-title: Crystal structure of the tetrameric fibrinogen-like recognition domain of fibrinogen C domain containing 1 (FIBCD1) protein publication-title: J. Biol. Chem contributor: fullname: Holmskov – volume: 266 start-page: 308 year: 1999 end-page: 314 ident: bib60 article-title: Deficient coacervation of two forms of human tropoelastin associated with supravalvular aortic stenosis publication-title: Eur. J. Biochem contributor: fullname: Weiss – volume: 167 start-page: 94 year: 2011 end-page: 103 ident: bib4 article-title: Coacervation of tropoelastin publication-title: Adv. Colloid Interface Sci contributor: fullname: Weiss – volume: 43 start-page: 769 year: 2006 end-page: 787 ident: bib45 article-title: The molecular genetics of Marfan syndrome and related disorders publication-title: J. Med. Genet contributor: fullname: Godfrey – volume: 283 start-page: 13874 year: 2008 end-page: 13888 ident: bib38 article-title: Targeting of bone morphogenetic protein growth factor complexes to fibrillin publication-title: J. Biol. Chem contributor: fullname: Sakai – volume: 325 start-page: 391 year: 1997 end-page: 400 ident: bib34 article-title: Asymmetry adjacent to the collagen-like domain in rat liver mannose-binding protein publication-title: Biochem. J contributor: fullname: Drickamer – volume: 173 start-page: 857 year: 1978 end-page: 862 ident: bib58 article-title: Elastin cross-linking publication-title: Biochem. J contributor: fullname: Cooper – volume: 274 start-page: 30196 year: 1999 end-page: 30201 ident: bib16 article-title: Angiopoietin-1 and -2 coiled coil domains mediate distinct homo-oligomerization patterns, but fibrinogen-like domains mediate ligand activity publication-title: J. Biol. Chem contributor: fullname: Yeilding – volume: 47 start-page: 1049 year: 1999 end-page: 1056 ident: bib24 article-title: Ultrastructural distribution of 36-kD microfibril-associated glycoprotein (MAGP-36) in human and bovine tissues publication-title: J. Histochem. Cytochem contributor: fullname: Kobayashi – volume: 1 start-page: 164 year: 2011 ident: bib26 article-title: Essential role of microfibrillar-associated protein 4 in human cutaneous homeostasis and in its photoprotection publication-title: Sci. Rep contributor: fullname: Takema – volume: 22 start-page: 195 year: 2006 end-page: 201 ident: bib27 article-title: The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling publication-title: Bioinformatics contributor: fullname: Schwede – volume: 281 start-page: 8016 year: 2006 end-page: 8023 ident: bib13 article-title: Fibrillins 1 and 2 perform partially overlapping functions during aortic development publication-title: J. Biol. Chem contributor: fullname: Ramirez – volume: 285 start-page: 1229 year: 2010 end-page: 1238 ident: bib49 article-title: The recognition unit of FIBCD1 organizes into a noncovalently linked tetrameric structure and uses a hydrophobic funnel (S1) for acetyl group recognition publication-title: J. Biol. Chem contributor: fullname: Holmskov – volume: 70 start-page: 862 year: 2015 end-page: 872 ident: bib64 article-title: Microfibrillar-associated protein 4 modulates airway smooth muscle cell phenotype in experimental asthma publication-title: Thorax contributor: fullname: Sorensen – volume: 8 start-page: e82383 year: 2013 ident: bib32 article-title: Enzyme-linked immunosorbent assay characterization of basal variation and heritability of systemic microfibrillar-associated protein 4 publication-title: PLoS One contributor: fullname: Sørensen – volume: 307 start-page: 224 year: 2005 end-page: 230 ident: bib21 article-title: 36-kDa microfibril-associated glycoprotein (MAGP-36) is an elastin-binding protein increased in chick aortae during development and growth publication-title: Exp. Cell Res contributor: fullname: Itano – volume: 106 start-page: 2503 year: 2002 end-page: 2509 ident: bib12 article-title: Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice publication-title: Circulation contributor: fullname: Soininen – volume: 102 start-page: 1783 year: 1998 end-page: 1787 ident: bib11 article-title: Novel arterial pathology in mice and humans hemizygous for elastin publication-title: J. Clin. Invest contributor: fullname: Keating – volume: 36 start-page: 178 year: 2004 end-page: 182 ident: bib54 article-title: Elastic fiber homeostasis requires lysyl oxidase-like 1 protein publication-title: Nat. Genet contributor: fullname: Li – volume: 179 start-page: 455 year: 2007 end-page: 462 ident: bib36 article-title: Localization and characterization of the mannose-binding lectin (MBL)-associated-serine protease-2 binding site in rat ficolin-A: equivalent binding sites within the collagenous domains of MBLs and ficolins publication-title: J. Immunol contributor: fullname: Wallis – volume: 9 start-page: 671 year: 2012 ident: 10.1074/jbc.M115.681775_bib42 article-title: NIH Image to ImageJ: 25 years of image analysis publication-title: Nat. Methods doi: 10.1038/nmeth.2089 contributor: fullname: Schneider – volume: 48 start-page: 369 year: 2011 ident: 10.1074/jbc.M115.681775_bib15 article-title: Ficolins and FIBCD1: soluble and membrane bound pattern recognition molecules with acetyl group selectivity publication-title: Mol. Immunol doi: 10.1016/j.molimm.2010.09.019 contributor: fullname: Thomsen – volume: 64 start-page: 104 year: 2006 ident: 10.1074/jbc.M115.681775_bib25 article-title: Microfibril-associated protein 4 binds to surfactant protein A (SP-A) and colocalizes with SP-A in the extracellular matrix of the lung publication-title: Scand. J. Immunol doi: 10.1111/j.1365-3083.2006.01778.x contributor: fullname: Schlosser – volume: 282 start-page: 8935 year: 2007 ident: 10.1074/jbc.M115.681775_bib47 article-title: Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin publication-title: J. Biol. Chem doi: 10.1074/jbc.M608204200 contributor: fullname: El-Hallous – volume: 44 start-page: 10271 year: 2005 ident: 10.1074/jbc.M115.681775_bib56 article-title: Coacervation is promoted by molecular interactions between the PF2 segment of fibrillin-1 and the domain 4 region of tropoelastin publication-title: Biochemistry doi: 10.1021/bi050530d contributor: fullname: Clarke – volume: 308 start-page: L1114 year: 2015 ident: 10.1074/jbc.M115.681775_bib65 article-title: Characterization of spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4 publication-title: Am. J. Physiol. Lung. Cell Mol. Physiol doi: 10.1152/ajplung.00351.2014 contributor: fullname: Holm – volume: 15 start-page: e8 year: 2013 ident: 10.1074/jbc.M115.681775_bib2 article-title: Elastic fibres in health and disease publication-title: Expert Rev. Mol. Med doi: 10.1017/erm.2013.9 contributor: fullname: Baldwin – volume: 39 start-page: 839 year: 2012 ident: 10.1074/jbc.M115.681775_bib51 article-title: Total desmosines in plasma and urine correlate with lung function publication-title: Eur. Respir. J doi: 10.1183/09031936.00064611 contributor: fullname: Lindberg – volume: 325 start-page: 391 year: 1997 ident: 10.1074/jbc.M115.681775_bib34 article-title: Asymmetry adjacent to the collagen-like domain in rat liver mannose-binding protein publication-title: Biochem. J doi: 10.1042/bj3250391 contributor: fullname: Wallis – volume: 70 start-page: 862 year: 2015 ident: 10.1074/jbc.M115.681775_bib64 article-title: Microfibrillar-associated protein 4 modulates airway smooth muscle cell phenotype in experimental asthma publication-title: Thorax doi: 10.1136/thoraxjnl-2014-206609 contributor: fullname: Pilecki – volume: 36 start-page: 178 year: 2004 ident: 10.1074/jbc.M115.681775_bib54 article-title: Elastic fiber homeostasis requires lysyl oxidase-like 1 protein publication-title: Nat. Genet doi: 10.1038/ng1297 contributor: fullname: Liu – volume: 282 start-page: 800 year: 2007 ident: 10.1074/jbc.M115.681775_bib9 article-title: Microfibril-associated MAGP-2 stimulates elastic fiber assembly publication-title: J. Biol. Chem doi: 10.1074/jbc.M609692200 contributor: fullname: Lemaire – volume: 1 start-page: 164 year: 2011 ident: 10.1074/jbc.M115.681775_bib26 article-title: Essential role of microfibrillar-associated protein 4 in human cutaneous homeostasis and in its photoprotection publication-title: Sci. Rep doi: 10.1038/srep00164 contributor: fullname: Kasamatsu – volume: 279 start-page: 23748 year: 2004 ident: 10.1074/jbc.M115.681775_bib7 article-title: Molecular basis of elastic fiber formation: critical interactions and a tropoelastin-fibrillin-1 cross-link publication-title: J. Biol. Chem doi: 10.1074/jbc.M400212200 contributor: fullname: Rock – volume: 78 start-page: 1606 year: 2000 ident: 10.1074/jbc.M115.681775_bib35 article-title: Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling publication-title: Biophys. J doi: 10.1016/S0006-3495(00)76713-0 contributor: fullname: Schuck – volume: 289 start-page: 2880 year: 2014 ident: 10.1074/jbc.M115.681775_bib17 article-title: Crystal structure of the tetrameric fibrinogen-like recognition domain of fibrinogen C domain containing 1 (FIBCD1) protein publication-title: J. Biol. Chem doi: 10.1074/jbc.M113.520577 contributor: fullname: Shrive – volume: 129 start-page: 1165 year: 1995 ident: 10.1074/jbc.M115.681775_bib44 article-title: Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils publication-title: J. Cell Biol doi: 10.1083/jcb.129.4.1165 contributor: fullname: Zhang – volume: 284 start-page: 24553 year: 2009 ident: 10.1074/jbc.M115.681775_bib8 article-title: Differential regulation of elastic fiber formation by fibulin-4 and -5 publication-title: J. Biol. Chem doi: 10.1074/jbc.M109.019364 contributor: fullname: Choudhury – volume: 98 start-page: 13519 year: 2001 ident: 10.1074/jbc.M115.681775_bib18 article-title: The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems publication-title: Proc. Natl. Acad. Sci. U.S.A doi: 10.1073/pnas.201523798 contributor: fullname: Kairies – volume: 282 start-page: 3889 year: 2007 ident: 10.1074/jbc.M115.681775_bib43 article-title: Trivalent recognition unit of innate immunity system: crystal structure of trimeric human M-ficolin fibrinogen-like domain publication-title: J. Biol. Chem doi: 10.1074/jbc.M608627200 contributor: fullname: Tanio – volume: 70 start-page: 21 year: 2015 ident: 10.1074/jbc.M115.681775_bib63 article-title: A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD publication-title: Thorax doi: 10.1136/thoraxjnl-2014-205091 contributor: fullname: Brandsma – volume: 102 start-page: 1783 year: 1998 ident: 10.1074/jbc.M115.681775_bib11 article-title: Novel arterial pathology in mice and humans hemizygous for elastin publication-title: J. Clin. Invest doi: 10.1172/JCI4487 contributor: fullname: Li – volume: 281 start-page: 21546 year: 2006 ident: 10.1074/jbc.M115.681775_bib39 article-title: Expression of type XXIII collagen mRNA and protein publication-title: J. Biol. Chem doi: 10.1074/jbc.M604131200 contributor: fullname: Koch – volume: 258 start-page: 104 year: 1996 ident: 10.1074/jbc.M115.681775_bib37 article-title: Fibrillin-1: organization in microfibrils and structural properties publication-title: J. Mol. Biol doi: 10.1006/jmbi.1996.0237 contributor: fullname: Reinhardt – volume: 283 start-page: 13874 year: 2008 ident: 10.1074/jbc.M115.681775_bib38 article-title: Targeting of bone morphogenetic protein growth factor complexes to fibrillin publication-title: J. Biol. Chem doi: 10.1074/jbc.M707820200 contributor: fullname: Sengle – volume: 167 start-page: 94 year: 2011 ident: 10.1074/jbc.M115.681775_bib4 article-title: Coacervation of tropoelastin publication-title: Adv. Colloid Interface Sci doi: 10.1016/j.cis.2010.10.003 contributor: fullname: Yeo – year: 1992 ident: 10.1074/jbc.M115.681775_bib33 contributor: fullname: Laue – volume: 22 start-page: 195 year: 2006 ident: 10.1074/jbc.M115.681775_bib27 article-title: The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling publication-title: Bioinformatics doi: 10.1093/bioinformatics/bti770 contributor: fullname: Arnold – volume: 18 start-page: 2714 year: 1997 ident: 10.1074/jbc.M115.681775_bib30 article-title: SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling publication-title: Electrophoresis doi: 10.1002/elps.1150181505 contributor: fullname: Guex – volume: 120 start-page: 983 year: 2009 ident: 10.1074/jbc.M115.681775_bib46 article-title: Proteomic analysis in aortic media of patients with Marfan syndrome reveals increased activity of calpain 2 in aortic aneurysms publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.108.843516 contributor: fullname: Pilop – volume: 108 start-page: 1336 year: 2014 ident: 10.1074/jbc.M115.681775_bib52 article-title: Microfibrillar-associated protein 4: a potential biomarker of chronic obstructive pulmonary disease publication-title: Respir. Med doi: 10.1016/j.rmed.2014.06.003 contributor: fullname: Johansson – volume: 285 start-page: 24943 year: 2010 ident: 10.1074/jbc.M115.681775_bib40 article-title: In vivo studies of mutant fibrillin-1 microfibrils publication-title: J. Biol. Chem doi: 10.1074/jbc.M110.130021 contributor: fullname: Charbonneau – volume: 31 start-page: 3381 year: 2003 ident: 10.1074/jbc.M115.681775_bib29 article-title: SWISS-MODEL: an automated protein homology-modeling server publication-title: Nucleic Acids Res doi: 10.1093/nar/gkg520 contributor: fullname: Schwede – volume: 179 start-page: 455 year: 2007 ident: 10.1074/jbc.M115.681775_bib36 article-title: Localization and characterization of the mannose-binding lectin (MBL)-associated-serine protease-2 binding site in rat ficolin-A: equivalent binding sites within the collagenous domains of MBLs and ficolins publication-title: J. Immunol doi: 10.4049/jimmunol.179.1.455 contributor: fullname: Girija – volume: 43 start-page: 769 year: 2006 ident: 10.1074/jbc.M115.681775_bib45 article-title: The molecular genetics of Marfan syndrome and related disorders publication-title: J. Med. Genet doi: 10.1136/jmg.2005.039669 contributor: fullname: Robinson – volume: 285 start-page: 1229 year: 2010 ident: 10.1074/jbc.M115.681775_bib49 article-title: The recognition unit of FIBCD1 organizes into a noncovalently linked tetrameric structure and uses a hydrophobic funnel (S1) for acetyl group recognition publication-title: J. Biol. Chem doi: 10.1074/jbc.M109.061523 contributor: fullname: Thomsen – volume: 183 start-page: 3800 year: 2009 ident: 10.1074/jbc.M115.681775_bib14 article-title: Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin publication-title: J. Immunol doi: 10.4049/jimmunol.0901526 contributor: fullname: Schlosser – volume: 402 start-page: 63 year: 2007 ident: 10.1074/jbc.M115.681775_bib59 article-title: Domains 16 and 17 of tropoelastin in elastic fibre formation publication-title: Biochem. J doi: 10.1042/BJ20061145 contributor: fullname: Wachi – volume: 274 start-page: 32234 year: 1999 ident: 10.1074/jbc.M115.681775_bib20 article-title: Microfibril-associated protein 4 is present in lung washings and binds to the collagen region of lung surfactant protein D publication-title: J. Biol. Chem doi: 10.1074/jbc.274.45.32234 contributor: fullname: Lausen – volume: 266 start-page: 308 year: 1999 ident: 10.1074/jbc.M115.681775_bib60 article-title: Deficient coacervation of two forms of human tropoelastin associated with supravalvular aortic stenosis publication-title: Eur. J. Biochem doi: 10.1046/j.1432-1327.1999.00891.x contributor: fullname: Wu – volume: 106 start-page: 19029 year: 2009 ident: 10.1074/jbc.M115.681775_bib10 article-title: Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase publication-title: Proc. Natl. Acad. Sci. U.S.A doi: 10.1073/pnas.0908268106 contributor: fullname: Horiguchi – volume: 307 start-page: 224 year: 2005 ident: 10.1074/jbc.M115.681775_bib21 article-title: 36-kDa microfibril-associated glycoprotein (MAGP-36) is an elastin-binding protein increased in chick aortae during development and growth publication-title: Exp. Cell Res doi: 10.1016/j.yexcr.2005.03.005 contributor: fullname: Toyoshima – volume: 176 start-page: 1061 year: 2007 ident: 10.1074/jbc.M115.681775_bib55 article-title: Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo publication-title: J. Cell Biol doi: 10.1083/jcb.200611026 contributor: fullname: Hirai – volume: 268 start-page: 10345 year: 1993 ident: 10.1074/jbc.M115.681775_bib5 article-title: Oxidation, cross-linking, and insolubilization of recombinant tropoelastin by purified lysyl oxidase publication-title: J. Biol. Chem doi: 10.1016/S0021-9258(18)82207-4 contributor: fullname: Bedell-Hogan – volume: 8 start-page: e82383 year: 2013 ident: 10.1074/jbc.M115.681775_bib32 article-title: Enzyme-linked immunosorbent assay characterization of basal variation and heritability of systemic microfibrillar-associated protein 4 publication-title: PLoS One doi: 10.1371/journal.pone.0082383 contributor: fullname: Saekmose – volume: 274 start-page: 30196 year: 1999 ident: 10.1074/jbc.M115.681775_bib16 article-title: Angiopoietin-1 and -2 coiled coil domains mediate distinct homo-oligomerization patterns, but fibrinogen-like domains mediate ligand activity publication-title: J. Biol. Chem doi: 10.1074/jbc.274.42.30196 contributor: fullname: Procopio – volume: 106 start-page: 2503 year: 2002 ident: 10.1074/jbc.M115.681775_bib12 article-title: Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice publication-title: Circulation doi: 10.1161/01.CIR.0000038109.84500.1E contributor: fullname: Mäki – volume: 264 start-page: 17437 year: 1989 ident: 10.1074/jbc.M115.681775_bib22 article-title: Isolation and characterization of a new 36-kDa microfibril-associated glycoprotein from porcine aorta publication-title: J. Biol. Chem doi: 10.1016/S0021-9258(18)71514-7 contributor: fullname: Kobayashi – volume: 8 start-page: e82243 year: 2013 ident: 10.1074/jbc.M115.681775_bib23 article-title: Localization of microfibrillar-associated protein 4 (MFAP4) in human tissues: clinical evaluation of serum MFAP4 and its association with various cardiovascular conditions publication-title: PLoS One doi: 10.1371/journal.pone.0082243 contributor: fullname: Wulf-Johansson – volume: 258 start-page: 1 year: 1998 ident: 10.1074/jbc.M115.681775_bib3 article-title: Biochemistry of tropoelastin publication-title: Eur. J. Biochem doi: 10.1046/j.1432-1327.1998.2580001.x contributor: fullname: Vrhovski – volume: 20 start-page: 82 year: 1995 ident: 10.1074/jbc.M115.681775_bib31 article-title: The Swiss-3DImage collection and PDB-Browser on the World-Wide Web publication-title: Trends Biochem. Sci doi: 10.1016/S0968-0004(00)88963-X contributor: fullname: Peitsch – volume: 37 start-page: D387 year: 2009 ident: 10.1074/jbc.M115.681775_bib28 article-title: The SWISS-MODEL Repository and associated resources publication-title: Nucleic Acids Res doi: 10.1093/nar/gkn750 contributor: fullname: Kiefer – volume: 47 start-page: 1049 year: 1999 ident: 10.1074/jbc.M115.681775_bib24 article-title: Ultrastructural distribution of 36-kD microfibril-associated glycoprotein (MAGP-36) in human and bovine tissues publication-title: J. Histochem. Cytochem doi: 10.1177/002215549904700809 contributor: fullname: Toyoshima – volume: 278 start-page: 2740 year: 2003 ident: 10.1074/jbc.M115.681775_bib41 article-title: Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences publication-title: J. Biol. Chem doi: 10.1074/jbc.M209201200 contributor: fullname: Charbonneau – volume: 81 start-page: 229 year: 2007 ident: 10.1074/jbc.M115.681775_bib1 article-title: New insights into elastic fiber assembly publication-title: Birth Defects Res. C. Embryo Today doi: 10.1002/bdrc.20111 contributor: fullname: Wagenseil – volume: 26 start-page: 623 year: 2007 ident: 10.1074/jbc.M115.681775_bib19 article-title: Structural insights into the innate immune recognition specificities of L- and H-ficolins publication-title: EMBO J doi: 10.1038/sj.emboj.7601500 contributor: fullname: Garlatti – volume: 339 start-page: 71 year: 2010 ident: 10.1074/jbc.M115.681775_bib6 article-title: Biogenesis and function of fibrillin assemblies publication-title: Cell Tissue Res doi: 10.1007/s00441-009-0822-x contributor: fullname: Ramirez – volume: 280 start-page: 42848 year: 2005 ident: 10.1074/jbc.M115.681775_bib53 article-title: The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers publication-title: J. Biol. Chem doi: 10.1074/jbc.M506832200 contributor: fullname: Thomassin – volume: 879 start-page: 1893 year: 2011 ident: 10.1074/jbc.M115.681775_bib50 article-title: Quantitation of desmosine and isodesmosine in urine, plasma, and sputum by LC-MS/MS as biomarkers for elastin degradation publication-title: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci doi: 10.1016/j.jchromb.2011.05.011 contributor: fullname: Ma – volume: 21 start-page: 1808 year: 2012 ident: 10.1074/jbc.M115.681775_bib48 article-title: Correlating structure and function during the evolution of fibrinogen-related domains publication-title: Protein Sci doi: 10.1002/pro.2177 contributor: fullname: Doolittle – volume: 281 start-page: 8016 year: 2006 ident: 10.1074/jbc.M115.681775_bib13 article-title: Fibrillins 1 and 2 perform partially overlapping functions during aortic development publication-title: J. Biol. Chem doi: 10.1074/jbc.M511599200 contributor: fullname: Carta – volume: 173 start-page: 857 year: 1978 ident: 10.1074/jbc.M115.681775_bib58 article-title: Elastin cross-linking in vitro: studies on factors influencing the formation of desmosines by lysyl oxidase action on tropoelastin publication-title: Biochem. J doi: 10.1042/bj1730857 contributor: fullname: Narayanan – volume: 70 start-page: 445 year: 2003 ident: 10.1074/jbc.M115.681775_bib57 article-title: Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties publication-title: Biopolymers doi: 10.1002/bip.10512 contributor: fullname: Bellingham – volume: 415 start-page: 168 year: 2002 ident: 10.1074/jbc.M115.681775_bib62 article-title: Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo publication-title: Nature doi: 10.1038/415168a contributor: fullname: Yanagisawa – volume: 415 start-page: 171 year: 2002 ident: 10.1074/jbc.M115.681775_bib61 article-title: Fibulin-5/DANCE is essential for elastogenesis in vivo publication-title: Nature doi: 10.1038/415171a contributor: fullname: Nakamura |
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Snippet | MFAP4 (microfibrillar-associated protein 4) is an extracellular glycoprotein found in elastic fibers without a clearly defined role in elastic fiber assembly.... |
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SubjectTerms | Amino Acid Substitution analytical ultracentrifugation Animals calcium-binding protein Carrier Proteins - chemistry Carrier Proteins - genetics Carrier Proteins - metabolism Desmosine - metabolism Elastic Tissue - metabolism elastin Extracellular Matrix Proteins - chemistry Extracellular Matrix Proteins - genetics Extracellular Matrix Proteins - metabolism fibrillin Fibrillin-1 Fibrillins Glycobiology and Extracellular Matrices Glycoproteins - chemistry Glycoproteins - genetics Glycoproteins - metabolism Humans Ligands Male Mice, Inbred C57BL Mice, Mutant Strains microfibrillar-associated protein 4 Microfibrils - metabolism Microfilament Proteins - chemistry Microfilament Proteins - genetics Microfilament Proteins - metabolism Models, Molecular Mutation Peptide Fragments - chemistry Peptide Fragments - genetics Peptide Fragments - metabolism Protein Interaction Domains and Motifs Protein Isoforms - chemistry Protein Isoforms - genetics Protein Isoforms - metabolism Protein Multimerization Protein Transport Recombinant Proteins - chemistry Recombinant Proteins - metabolism site-directed mutagenesis surface plasmon resonance (SPR) Tropoelastin - chemistry Tropoelastin - genetics Tropoelastin - metabolism |
Title | Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation |
URI | https://dx.doi.org/10.1074/jbc.M115.681775 https://www.ncbi.nlm.nih.gov/pubmed/26601954 https://pubmed.ncbi.nlm.nih.gov/PMC4714194 |
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