Secretory Stanniocalcin 1 promotes metastasis of hepatocellular carcinoma through activation of JNK signaling pathway - Chan, Kristy Kwan-Shuen; Leung, Carmen Oi-Ning; Wong, Carmen Chak-Lui; Ho, Daniel Wai-Hung; Chok, Kenneth Siu-Ho; Lai, Ching-Lung; Ng, Irene Oi-Lin; Lo, Regina Cheuk-Lam (Cancer letters, 2017)
Keywords: Animals; Antineoplastic Agents - pharmacology; Biomarkers, Tumor - blood; Biomarkers, Tumor - genetics; Biomarkers, Tumor - metabolism; Biomarkers, Tumor - secretion; Breast cancer; c-Jun protein; Carcinoma, Hepatocellular - enzymology; Carcinoma, Hepatocellular - genetics; Carcinoma, Hepatocellular - secondary; Carcinoma, Hepatocellular - secretion; Cell migration; Cell Movement - drug effects; Cloning; Disease-Free Survival; Gene expression; Gene Expression Regulation, Neoplastic; Glycoproteins - blood; Glycoproteins - genetics; Glycoproteins - metabolism; Glycoproteins - secretion; HCC; Hepatocellular carcinoma; Humans; Hypoxia; JNK; JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors; JNK Mitogen-Activated Protein Kinases - metabolism; Kaplan-Meier Estimate; Liver cancer; Liver Neoplasms - enzymology; Liver Neoplasms - genetics; Liver Neoplasms - pathology; Liver Neoplasms - secretion; Lung Neoplasms - enzymology; Lung Neoplasms - genetics; Lung Neoplasms - secondary; Lung Neoplasms - secretion; Metastases; Metastasis; Mice, Inbred BALB C; Mice, Nude; Ovarian cancer; Phosphorylation; Protein Kinase Inhibitors - pharmacology; Proteins; RNA Interference; Rodents; Signal transduction; Signal Transduction - drug effects; Stanniocalcin; STC1; Time Factors; Transcription factors; Transfection; Tumor Burden; Tumor Hypoxia; Tumor Microenvironment; Up-Regulation; United States--US; STC1; HCC; JNK