Plasma concentrations of fibrinolytic factors in the subacute phase of myocardial infarction predict recurrent myocardial infarction or sudden cardiac death
Background: The prognostic value of plasma concentrations of tissue type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and C-reactive protein has been reported in patients with coronary artery disease. However, the association between cardiac events and these factors durin...
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Published in | International journal of cardiology Vol. 85; no. 2; pp. 277 - 283 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
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Elsevier Ireland Ltd
01.10.2002
Elsevier Science |
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Abstract | Background: The prognostic value of plasma concentrations of tissue type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and C-reactive protein has been reported in patients with coronary artery disease. However, the association between cardiac events and these factors during the acute and subacute phases of myocardial infarction (MI) is unknown. The purpose of this study was to determine whether elevated plasma concentrations of t-PA, PAI-1, and C-reactive protein in patients with MI are associated with future recurrent MI or sudden cardiac death.
Methods: We studied 106 consecutive patients who survived a confirmed first MI between 1993 and 1998 in our hospital. The control group consisted of 50 patients who had no significant coronary artery stenosis. Blood samples were obtained at the time of admission for acute MI and on the 28th day after admission. Patients were followed for a mean of 50 months after these measurements. The primary end points were sudden cardiac death and fatal or nonfatal acute MI.
Results: Of the 92 patients who were available for follow-up, 10 had cardiac events. Both the plasma t-PA and PAI-1 concentrations were elevated on day 1 of acute MI compared to the control group and decreased by day 28, but remained higher than those in the controls. Plasma C-reactive protein concentration was also elevated on day 1 and decreased by day 28. Using a stepwise variable choice model of Cox proportional hazards analysis including these fibrinolytic factors and C-reactive protein, only the t-PA concentration in the subacute phase was a significant predictor of cardiac events (relative risk per S.D. 3.20,
P<0.01). We further found that independent of other risk factors, an elevated t-PA concentration was predictive of cardiac events.
Conclusions: This study reveals that a rise in endogenous t-PA concentration during the subacute phase of MI could predict recurrent MI or sudden cardiac death. |
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AbstractList | The prognostic value of plasma concentrations of tissue type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and C-reactive protein has been reported in patients with coronary artery disease. However, the association between cardiac events and these factors during the acute and subacute phases of myocardial infarction (MI) is unknown. The purpose of this study was to determine whether elevated plasma concentrations of t-PA, PAI-1, and C-reactive protein in patients with MI are associated with future recurrent MI or sudden cardiac death.
We studied 106 consecutive patients who survived a confirmed first MI between 1993 and 1998 in our hospital. The control group consisted of 50 patients who had no significant coronary artery stenosis. Blood samples were obtained at the time of admission for acute MI and on the 28th day after admission. Patients were followed for a mean of 50 months after these measurements. The primary end points were sudden cardiac death and fatal or nonfatal acute MI.
Of the 92 patients who were available for follow-up, 10 had cardiac events. Both the plasma t-PA and PAI-1 concentrations were elevated on day 1 of acute MI compared to the control group and decreased by day 28, but remained higher than those in the controls. Plasma C-reactive protein concentration was also elevated on day 1 and decreased by day 28. Using a stepwise variable choice model of Cox proportional hazards analysis including these fibrinolytic factors and C-reactive protein, only the t-PA concentration in the subacute phase was a significant predictor of cardiac events (relative risk per S.D. 3.20, P<0.01). We further found that independent of other risk factors, an elevated t-PA concentration was predictive of cardiac events.
This study reveals that a rise in endogenous t-PA concentration during the subacute phase of MI could predict recurrent MI or sudden cardiac death. BACKGROUNDThe prognostic value of plasma concentrations of tissue type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and C-reactive protein has been reported in patients with coronary artery disease. However, the association between cardiac events and these factors during the acute and subacute phases of myocardial infarction (MI) is unknown. The purpose of this study was to determine whether elevated plasma concentrations of t-PA, PAI-1, and C-reactive protein in patients with MI are associated with future recurrent MI or sudden cardiac death. METHODSWe studied 106 consecutive patients who survived a confirmed first MI between 1993 and 1998 in our hospital. The control group consisted of 50 patients who had no significant coronary artery stenosis. Blood samples were obtained at the time of admission for acute MI and on the 28th day after admission. Patients were followed for a mean of 50 months after these measurements. The primary end points were sudden cardiac death and fatal or nonfatal acute MI. RESULTSOf the 92 patients who were available for follow-up, 10 had cardiac events. Both the plasma t-PA and PAI-1 concentrations were elevated on day 1 of acute MI compared to the control group and decreased by day 28, but remained higher than those in the controls. Plasma C-reactive protein concentration was also elevated on day 1 and decreased by day 28. Using a stepwise variable choice model of Cox proportional hazards analysis including these fibrinolytic factors and C-reactive protein, only the t-PA concentration in the subacute phase was a significant predictor of cardiac events (relative risk per S.D. 3.20, P<0.01). We further found that independent of other risk factors, an elevated t-PA concentration was predictive of cardiac events. CONCLUSIONSThis study reveals that a rise in endogenous t-PA concentration during the subacute phase of MI could predict recurrent MI or sudden cardiac death. Background: The prognostic value of plasma concentrations of tissue type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and C-reactive protein has been reported in patients with coronary artery disease. However, the association between cardiac events and these factors during the acute and subacute phases of myocardial infarction (MI) is unknown. The purpose of this study was to determine whether elevated plasma concentrations of t-PA, PAI-1, and C-reactive protein in patients with MI are associated with future recurrent MI or sudden cardiac death. Methods: We studied 106 consecutive patients who survived a confirmed first MI between 1993 and 1998 in our hospital. The control group consisted of 50 patients who had no significant coronary artery stenosis. Blood samples were obtained at the time of admission for acute MI and on the 28th day after admission. Patients were followed for a mean of 50 months after these measurements. The primary end points were sudden cardiac death and fatal or nonfatal acute MI. Results: Of the 92 patients who were available for follow-up, 10 had cardiac events. Both the plasma t-PA and PAI-1 concentrations were elevated on day 1 of acute MI compared to the control group and decreased by day 28, but remained higher than those in the controls. Plasma C-reactive protein concentration was also elevated on day 1 and decreased by day 28. Using a stepwise variable choice model of Cox proportional hazards analysis including these fibrinolytic factors and C-reactive protein, only the t-PA concentration in the subacute phase was a significant predictor of cardiac events (relative risk per S.D. 3.20, P<0.01). We further found that independent of other risk factors, an elevated t-PA concentration was predictive of cardiac events. Conclusions: This study reveals that a rise in endogenous t-PA concentration during the subacute phase of MI could predict recurrent MI or sudden cardiac death. |
Author | Soeki, Takeshi Shinohara, Hisanori Tamura, Yoshiyuki Fukuda, Nobuo Sakabe, Koichi Onose, Yukiko |
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Cites_doi | 10.1182/blood.V69.2.381.381 10.1093/oxfordjournals.eurheartj.a059862 10.1016/0002-8703(92)90592-J 10.1016/0140-6736(93)90998-V 10.1016/S0140-6736(87)93050-9 10.1161/01.CIR.94.9.2057 10.1253/jcj.63.976 10.1016/0014-4827(92)90101-D 10.1253/jcj.61.308 10.1056/NEJM199201303260506 10.1161/01.CIR.95.10.2380 10.1182/blood.V69.5.1354.1354 10.1016/0049-3848(87)90147-2 10.1016/S0140-6736(96)07591-5 10.1096/fasebj.5.8.1850705 10.1056/NEJM199704033361401 10.1016/0955-0674(95)80116-2 10.1016/S0735-1097(98)00250-2 10.1056/NEJM198403223101204 10.1161/01.CIR.97.20.2007 10.1016/S0021-9258(18)67293-X 10.1016/0021-9150(90)90056-O 10.1056/NEJM199503093321003 10.1055/s-0038-1646605 10.1136/hrt.80.4.334 10.1016/0002-8703(95)90191-4 10.1002/bies.950140705 10.1055/s-0038-1645996 10.1182/blood.V71.1.220.bloodjournal711220 10.1016/S0167-5273(01)00515-0 10.1111/j.1365-2141.1988.tb02490.x 10.1056/NEJM199408183310701 10.1055/s-0037-1615382 10.1016/0735-1097(94)90543-6 |
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Keywords | Plasminogen activator inhibitor-1 (PAI-1) Tissue type plasminogen activator (t-PA) C-reactive protein Myocardial infarction (MI) Human Recurrence Prognosis Serine endopeptidases Infarct Enzyme Acute Sudden death Biological marker Cardiovascular disease Exploration Coronary heart disease Myocardial disease Fibrinolysis t-Plasminogen activator Peptidases Plasminogen activator inhibitor 1 Risk factor Myocardium Hydrolases Complication C reactive protein |
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References | Fuster, Badimon, Badimon, Chesebro (BIB18) 1992; 326 Ridker, Vaughan, Stampfer, Manson, Hennekens (BIB11) 1993; 341 Jansson, Nilsson, Johnson (BIB13) 1998; 80 Miyamoto, Ogawa, Sakamoto (BIB34) 2001; 80 Wright, Flapan, Alberti, Ludlam, Fox (BIB20) 1994; 24 Thompson, Kienast, Pyke, Haverkate, van de Loo (BIB7) 1995; 332 Kai, Ikeda, Yasukawa (BIB31) 1998; 32 Sprengers, Kluft (BIB2) 1987; 69 (BIB17) 1984; 310 Wun, Capuano (BIB3) 1987; 69 Matrisian (BIB28) 1992; 14 Birkedal-Hansen (BIB30) 1995; 7 Salonen, Salonen (BIB32) 1990; 81 Ridker, Cushman, Stampfer, Tracy, Hennekens (BIB15) 1997; 336 Liuzzo, Biasucci, Gallimore (BIB35) 1994; 331 Held, Hjemdahl, Rehnqvist (BIB10) 1997; 95 Declerck, Alessi, Verstreken, Kruithof, Juhan-Vague, Collen (BIB24) 1988; 71 Booth, Simpson, Croll, Bennett, MacGregor (BIB25) 1988; 70 Almer, Ohlin (BIB4) 1987; 47 Hirashima, Ogawa, Oshima (BIB19) 1995; 130 Masuda, Yasue, Ogawa (BIB26) 1992; 124 Hamsten, De Faire, Walldius (BIB12) 1987; 2 Juhan-Vague, Pyke, Alessi, Jespersen, Haverkate, Thompson (BIB8) 1996; 94 Rijken, Juhan-Vague, Collen (BIB22) 1983; 101 Ridker, Glynn, Hennekens (BIB16) 1998; 97 Nordt, Moser, Kohler (BIB33) 1998; 80 Haverkate, Thompson, Pyke, Gallimore, Pepys (BIB14) 1997; 349 Ranby, Nguyen, Scarabin, Samama (BIB23) 1989; 61 Keski-Oja, Lohi, Tuuttila, Tryggvason, Vartio (BIB29) 1992; 202 Soeki, Tamura, Shinohara (BIB9) 1999; 63 Hajjar, Harpel, Jaffer, Nachman (BIB1) 1986; 261 Woessner (BIB27) 1991; 5 Jansson, Nilsson, Olofsson (BIB6) 1991; 12 Moriyama, Ogawa, Oshima (BIB21) 1997; 61 Gram, Kluft, Jespersen (BIB5) 1987; 58 Miyamoto (10.1016/S0167-5273(02)00186-9_BIB34) 2001; 80 Thompson (10.1016/S0167-5273(02)00186-9_BIB7) 1995; 332 Ranby (10.1016/S0167-5273(02)00186-9_BIB23) 1989; 61 Almer (10.1016/S0167-5273(02)00186-9_BIB4) 1987; 47 Masuda (10.1016/S0167-5273(02)00186-9_BIB26) 1992; 124 Matrisian (10.1016/S0167-5273(02)00186-9_BIB28) 1992; 14 Woessner (10.1016/S0167-5273(02)00186-9_BIB27) 1991; 5 Declerck (10.1016/S0167-5273(02)00186-9_BIB24) 1988; 71 Gram (10.1016/S0167-5273(02)00186-9_BIB5) 1987; 58 (10.1016/S0167-5273(02)00186-9_BIB17) 1984; 310 Jansson (10.1016/S0167-5273(02)00186-9_BIB6) 1991; 12 Jansson (10.1016/S0167-5273(02)00186-9_BIB13) 1998; 80 Hamsten (10.1016/S0167-5273(02)00186-9_BIB12) 1987; 2 Held (10.1016/S0167-5273(02)00186-9_BIB10) 1997; 95 Moriyama (10.1016/S0167-5273(02)00186-9_BIB21) 1997; 61 Hirashima (10.1016/S0167-5273(02)00186-9_BIB19) 1995; 130 Booth (10.1016/S0167-5273(02)00186-9_BIB25) 1988; 70 Birkedal-Hansen (10.1016/S0167-5273(02)00186-9_BIB30) 1995; 7 Rijken (10.1016/S0167-5273(02)00186-9_BIB22) 1983; 101 Haverkate (10.1016/S0167-5273(02)00186-9_BIB14) 1997; 349 Nordt (10.1016/S0167-5273(02)00186-9_BIB33) 1998; 80 Liuzzo (10.1016/S0167-5273(02)00186-9_BIB35) 1994; 331 Salonen (10.1016/S0167-5273(02)00186-9_BIB32) 1990; 81 Sprengers (10.1016/S0167-5273(02)00186-9_BIB2) 1987; 69 Keski-Oja (10.1016/S0167-5273(02)00186-9_BIB29) 1992; 202 Fuster (10.1016/S0167-5273(02)00186-9_BIB18) 1992; 326 Kai (10.1016/S0167-5273(02)00186-9_BIB31) 1998; 32 Wun (10.1016/S0167-5273(02)00186-9_BIB3) 1987; 69 Ridker (10.1016/S0167-5273(02)00186-9_BIB11) 1993; 341 Juhan-Vague (10.1016/S0167-5273(02)00186-9_BIB8) 1996; 94 Hajjar (10.1016/S0167-5273(02)00186-9_BIB1) 1986; 261 Ridker (10.1016/S0167-5273(02)00186-9_BIB15) 1997; 336 Wright (10.1016/S0167-5273(02)00186-9_BIB20) 1994; 24 Ridker (10.1016/S0167-5273(02)00186-9_BIB16) 1998; 97 Soeki (10.1016/S0167-5273(02)00186-9_BIB9) 1999; 63 |
References_xml | – volume: 202 start-page: 471 year: 1992 end-page: 476 ident: BIB29 article-title: Proteolytic processing of the 72,000-Da type IV collagenase by urokinase plasminogen activator publication-title: Exp Cell Res contributor: fullname: Vartio – volume: 80 start-page: 334 year: 1998 end-page: 337 ident: BIB13 article-title: von Willebrand factor, tissue plasminogen activator, and dehydroepiandrosterone sulfate predict cardiovascular death in a 10-year follow up of survivors of acute myocardial infarction publication-title: Heart contributor: fullname: Johnson – volume: 14 start-page: 455 year: 1992 end-page: 463 ident: BIB28 article-title: The matrix-degrading metalloproteinases publication-title: Bioessays contributor: fullname: Matrisian – volume: 124 start-page: 314 year: 1992 end-page: 319 ident: BIB26 article-title: Plasma plasminogen activator inhibitor activity and tissue plasminogen activator levels in patients with unstable angina and those with coronary spastic angina publication-title: Am Heart J contributor: fullname: Ogawa – volume: 349 start-page: 462 year: 1997 end-page: 466 ident: BIB14 article-title: Production of C-reactive protein and risk of coronary events in stable and unstable angina publication-title: Lancet contributor: fullname: Pepys – volume: 61 start-page: 308 year: 1997 end-page: 314 ident: BIB21 article-title: Captoril reduced plasminogen activator inhibitor activity in patients with acute myocardial infarction publication-title: Jpn Circ J contributor: fullname: Oshima – volume: 70 start-page: 327 year: 1988 end-page: 333 ident: BIB25 article-title: Plasminogen activator inhibitor (PAI-1) in plasma and platelets publication-title: Br J Haematol contributor: fullname: MacGregor – volume: 69 start-page: 381 year: 1987 end-page: 387 ident: BIB2 article-title: Plasminogen activator inhibitors publication-title: Blood contributor: fullname: Kluft – volume: 80 start-page: 235 year: 2001 end-page: 242 ident: BIB34 article-title: Platelet hyperaggregability persists even after the improvement of increased blood coagulation and impaired fibrinolysis with the stabilization of symptoms in patients with unstable angina publication-title: Int J Cardiol contributor: fullname: Sakamoto – volume: 69 start-page: 1354 year: 1987 end-page: 1362 ident: BIB3 article-title: Initiation and regulation of fibrinolysis in human plasma at the plasminogen activator level publication-title: Blood contributor: fullname: Capuano – volume: 12 start-page: 157 year: 1991 end-page: 161 ident: BIB6 article-title: Tissue plasminogen activator and other risk factors as predictors of cardiovascular events in patients with severe angina pectoris publication-title: Eur Heart J contributor: fullname: Olofsson – volume: 341 start-page: 1165 year: 1993 end-page: 1168 ident: BIB11 article-title: Endogenous tissue type plasminogen activator and risk of myocardial infarction publication-title: Lancet contributor: fullname: Hennekens – volume: 81 start-page: 33 year: 1990 end-page: 40 ident: BIB32 article-title: Progression of carotid atherosclerosis and its determinants: a population-based ultrasonography study publication-title: Atherosclerosis contributor: fullname: Salonen – volume: 63 start-page: 976 year: 1999 end-page: 980 ident: BIB9 article-title: Fibrinolytic factors, serum lipid and C-reactive protein predicting cardiac events in Japanese patients with coronary atherosclerotic lesions publication-title: Jpn Circ J contributor: fullname: Shinohara – volume: 326 start-page: 310 year: 1992 end-page: 318 ident: BIB18 article-title: The pathogenesis of coronary artery disease and the acute coronary syndromes publication-title: New Engl J Med contributor: fullname: Chesebro – volume: 2 start-page: 3 year: 1987 end-page: 9 ident: BIB12 article-title: Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction publication-title: Lancet contributor: fullname: Walldius – volume: 47 start-page: 335 year: 1987 end-page: 339 ident: BIB4 article-title: Elevated levels of the rapid inhibitor of plasminogen activator (t-PAI) in acute myocardial infarction publication-title: Thromb Res contributor: fullname: Ohlin – volume: 58 start-page: 817 year: 1987 end-page: 821 ident: BIB5 article-title: Depression of tissue plasminogen activator (t-PA) activity and rise of t-PA inhibition and acute-phase reactants in blood of patients with acute myocardial infarction (AMI) publication-title: Thromb Haemost contributor: fullname: Jespersen – volume: 336 start-page: 973 year: 1997 end-page: 979 ident: BIB15 article-title: Inflammation, aspirin, and risks of cardiovascular disease in apparently healthy men publication-title: New Engl J Med contributor: fullname: Hennekens – volume: 71 start-page: 220 year: 1988 end-page: 225 ident: BIB24 article-title: Measurement of plasminogen activator inhibitor 1 in biological fluids with a murine monoclonal antibody-based enzyme-linked immunosorbent assay publication-title: Blood contributor: fullname: Collen – volume: 331 start-page: 417 year: 1994 end-page: 424 ident: BIB35 article-title: The prognostic value of C-reactive protein and serum amyloid A protein in severe unstable angina publication-title: New Engl J Med contributor: fullname: Gallimore – volume: 5 start-page: 2145 year: 1991 end-page: 2154 ident: BIB27 article-title: Matrix metalloproteinases and their inhibitors in connective tissue remodeling publication-title: FASEB J contributor: fullname: Woessner – volume: 80 start-page: 881 year: 1998 end-page: 886 ident: BIB33 article-title: Augmented platelet aggregation as predictor of reocclusion after thrombolysis in acute myocardial infarction publication-title: Thromb Haemost contributor: fullname: Kohler – volume: 97 start-page: 2007 year: 1998 end-page: 2011 ident: BIB16 article-title: C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction publication-title: Circulation contributor: fullname: Hennekens – volume: 61 start-page: 409 year: 1989 end-page: 414 ident: BIB23 article-title: Immunoreactivity of tissue plasminogen activator and its inhibitor complexes. Biochemical and multicenter validation of a two-site immunosorbent assay publication-title: Thromb Haemost contributor: fullname: Samama – volume: 95 start-page: 2380 year: 1997 end-page: 2386 ident: BIB10 article-title: Fibrinolytic variables and cardiovascular prognosis in patients with stable angina pectoris treated with verapamil or metoprolol. Results from the Angina Prognosis study in Stockholm publication-title: Circulation contributor: fullname: Rehnqvist – volume: 24 start-page: 67 year: 1994 end-page: 73 ident: BIB20 article-title: Effects of captopril therapy on endogenous fibrinolysis in men with recent, uncomplicated myocardial infarction publication-title: J Am Coll Cardiol contributor: fullname: Fox – volume: 261 start-page: 11656 year: 1986 end-page: 11662 ident: BIB1 article-title: Binding of plasminogen to cultured human endothelial cells publication-title: J Biol Chem contributor: fullname: Nachman – volume: 7 start-page: 728 year: 1995 end-page: 735 ident: BIB30 article-title: Proteolytic remodeling of extracellular matrix publication-title: Curr Opin Cell Biol contributor: fullname: Birkedal-Hansen – volume: 310 start-page: 750 year: 1984 end-page: 758 ident: BIB17 article-title: Myocardial infarction and mortality in the Coronary Artery Surgery Study (CASS) randomized trial publication-title: New Engl J Med – volume: 94 start-page: 2057 year: 1996 end-page: 2063 ident: BIB8 article-title: Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris publication-title: Circulation contributor: fullname: Thompson – volume: 130 start-page: 933 year: 1995 end-page: 939 ident: BIB19 article-title: Serial changes of plasminogen activator inhibitor activity in acute myocardial infarction: difference between thrombolytic therapy and direct coronary angioplasty publication-title: Am Heart J contributor: fullname: Oshima – volume: 332 start-page: 635 year: 1995 end-page: 641 ident: BIB7 article-title: Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris publication-title: New Engl J Med contributor: fullname: van de Loo – volume: 32 start-page: 368 year: 1998 end-page: 372 ident: BIB31 article-title: Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes publication-title: J Am Coll Cardiol contributor: fullname: Yasukawa – volume: 101 start-page: 285 year: 1983 end-page: 294 ident: BIB22 article-title: Complexes between tissue-type plasminogen activator and proteinase inhibitors in human plasma, identified with an immunoradiometric assay publication-title: J Lab Clin Med contributor: fullname: Collen – volume: 69 start-page: 381 year: 1987 ident: 10.1016/S0167-5273(02)00186-9_BIB2 article-title: Plasminogen activator inhibitors publication-title: Blood doi: 10.1182/blood.V69.2.381.381 contributor: fullname: Sprengers – volume: 12 start-page: 157 year: 1991 ident: 10.1016/S0167-5273(02)00186-9_BIB6 article-title: Tissue plasminogen activator and other risk factors as predictors of cardiovascular events in patients with severe angina pectoris publication-title: Eur Heart J doi: 10.1093/oxfordjournals.eurheartj.a059862 contributor: fullname: Jansson – volume: 124 start-page: 314 year: 1992 ident: 10.1016/S0167-5273(02)00186-9_BIB26 article-title: Plasma plasminogen activator inhibitor activity and tissue plasminogen activator levels in patients with unstable angina and those with coronary spastic angina publication-title: Am Heart J doi: 10.1016/0002-8703(92)90592-J contributor: fullname: Masuda – volume: 341 start-page: 1165 year: 1993 ident: 10.1016/S0167-5273(02)00186-9_BIB11 article-title: Endogenous tissue type plasminogen activator and risk of myocardial infarction publication-title: Lancet doi: 10.1016/0140-6736(93)90998-V contributor: fullname: Ridker – volume: 2 start-page: 3 year: 1987 ident: 10.1016/S0167-5273(02)00186-9_BIB12 article-title: Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction publication-title: Lancet doi: 10.1016/S0140-6736(87)93050-9 contributor: fullname: Hamsten – volume: 94 start-page: 2057 year: 1996 ident: 10.1016/S0167-5273(02)00186-9_BIB8 article-title: Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris publication-title: Circulation doi: 10.1161/01.CIR.94.9.2057 contributor: fullname: Juhan-Vague – volume: 63 start-page: 976 year: 1999 ident: 10.1016/S0167-5273(02)00186-9_BIB9 article-title: Fibrinolytic factors, serum lipid and C-reactive protein predicting cardiac events in Japanese patients with coronary atherosclerotic lesions publication-title: Jpn Circ J doi: 10.1253/jcj.63.976 contributor: fullname: Soeki – volume: 202 start-page: 471 year: 1992 ident: 10.1016/S0167-5273(02)00186-9_BIB29 article-title: Proteolytic processing of the 72,000-Da type IV collagenase by urokinase plasminogen activator publication-title: Exp Cell Res doi: 10.1016/0014-4827(92)90101-D contributor: fullname: Keski-Oja – volume: 61 start-page: 308 year: 1997 ident: 10.1016/S0167-5273(02)00186-9_BIB21 article-title: Captoril reduced plasminogen activator inhibitor activity in patients with acute myocardial infarction publication-title: Jpn Circ J doi: 10.1253/jcj.61.308 contributor: fullname: Moriyama – volume: 326 start-page: 310 year: 1992 ident: 10.1016/S0167-5273(02)00186-9_BIB18 article-title: The pathogenesis of coronary artery disease and the acute coronary syndromes publication-title: New Engl J Med doi: 10.1056/NEJM199201303260506 contributor: fullname: Fuster – volume: 95 start-page: 2380 year: 1997 ident: 10.1016/S0167-5273(02)00186-9_BIB10 article-title: Fibrinolytic variables and cardiovascular prognosis in patients with stable angina pectoris treated with verapamil or metoprolol. Results from the Angina Prognosis study in Stockholm publication-title: Circulation doi: 10.1161/01.CIR.95.10.2380 contributor: fullname: Held – volume: 69 start-page: 1354 year: 1987 ident: 10.1016/S0167-5273(02)00186-9_BIB3 article-title: Initiation and regulation of fibrinolysis in human plasma at the plasminogen activator level publication-title: Blood doi: 10.1182/blood.V69.5.1354.1354 contributor: fullname: Wun – volume: 47 start-page: 335 year: 1987 ident: 10.1016/S0167-5273(02)00186-9_BIB4 article-title: Elevated levels of the rapid inhibitor of plasminogen activator (t-PAI) in acute myocardial infarction publication-title: Thromb Res doi: 10.1016/0049-3848(87)90147-2 contributor: fullname: Almer – volume: 349 start-page: 462 year: 1997 ident: 10.1016/S0167-5273(02)00186-9_BIB14 article-title: Production of C-reactive protein and risk of coronary events in stable and unstable angina publication-title: Lancet doi: 10.1016/S0140-6736(96)07591-5 contributor: fullname: Haverkate – volume: 5 start-page: 2145 year: 1991 ident: 10.1016/S0167-5273(02)00186-9_BIB27 article-title: Matrix metalloproteinases and their inhibitors in connective tissue remodeling publication-title: FASEB J doi: 10.1096/fasebj.5.8.1850705 contributor: fullname: Woessner – volume: 336 start-page: 973 year: 1997 ident: 10.1016/S0167-5273(02)00186-9_BIB15 article-title: Inflammation, aspirin, and risks of cardiovascular disease in apparently healthy men publication-title: New Engl J Med doi: 10.1056/NEJM199704033361401 contributor: fullname: Ridker – volume: 101 start-page: 285 year: 1983 ident: 10.1016/S0167-5273(02)00186-9_BIB22 article-title: Complexes between tissue-type plasminogen activator and proteinase inhibitors in human plasma, identified with an immunoradiometric assay publication-title: J Lab Clin Med contributor: fullname: Rijken – volume: 7 start-page: 728 year: 1995 ident: 10.1016/S0167-5273(02)00186-9_BIB30 article-title: Proteolytic remodeling of extracellular matrix publication-title: Curr Opin Cell Biol doi: 10.1016/0955-0674(95)80116-2 contributor: fullname: Birkedal-Hansen – volume: 32 start-page: 368 year: 1998 ident: 10.1016/S0167-5273(02)00186-9_BIB31 article-title: Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes publication-title: J Am Coll Cardiol doi: 10.1016/S0735-1097(98)00250-2 contributor: fullname: Kai – volume: 310 start-page: 750 year: 1984 ident: 10.1016/S0167-5273(02)00186-9_BIB17 article-title: Myocardial infarction and mortality in the Coronary Artery Surgery Study (CASS) randomized trial publication-title: New Engl J Med doi: 10.1056/NEJM198403223101204 – volume: 97 start-page: 2007 year: 1998 ident: 10.1016/S0167-5273(02)00186-9_BIB16 article-title: C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction publication-title: Circulation doi: 10.1161/01.CIR.97.20.2007 contributor: fullname: Ridker – volume: 261 start-page: 11656 year: 1986 ident: 10.1016/S0167-5273(02)00186-9_BIB1 article-title: Binding of plasminogen to cultured human endothelial cells publication-title: J Biol Chem doi: 10.1016/S0021-9258(18)67293-X contributor: fullname: Hajjar – volume: 81 start-page: 33 year: 1990 ident: 10.1016/S0167-5273(02)00186-9_BIB32 article-title: Progression of carotid atherosclerosis and its determinants: a population-based ultrasonography study publication-title: Atherosclerosis doi: 10.1016/0021-9150(90)90056-O contributor: fullname: Salonen – volume: 332 start-page: 635 year: 1995 ident: 10.1016/S0167-5273(02)00186-9_BIB7 article-title: Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris publication-title: New Engl J Med doi: 10.1056/NEJM199503093321003 contributor: fullname: Thompson – volume: 61 start-page: 409 year: 1989 ident: 10.1016/S0167-5273(02)00186-9_BIB23 article-title: Immunoreactivity of tissue plasminogen activator and its inhibitor complexes. Biochemical and multicenter validation of a two-site immunosorbent assay publication-title: Thromb Haemost doi: 10.1055/s-0038-1646605 contributor: fullname: Ranby – volume: 80 start-page: 334 year: 1998 ident: 10.1016/S0167-5273(02)00186-9_BIB13 article-title: von Willebrand factor, tissue plasminogen activator, and dehydroepiandrosterone sulfate predict cardiovascular death in a 10-year follow up of survivors of acute myocardial infarction publication-title: Heart doi: 10.1136/hrt.80.4.334 contributor: fullname: Jansson – volume: 130 start-page: 933 year: 1995 ident: 10.1016/S0167-5273(02)00186-9_BIB19 article-title: Serial changes of plasminogen activator inhibitor activity in acute myocardial infarction: difference between thrombolytic therapy and direct coronary angioplasty publication-title: Am Heart J doi: 10.1016/0002-8703(95)90191-4 contributor: fullname: Hirashima – volume: 14 start-page: 455 year: 1992 ident: 10.1016/S0167-5273(02)00186-9_BIB28 article-title: The matrix-degrading metalloproteinases publication-title: Bioessays doi: 10.1002/bies.950140705 contributor: fullname: Matrisian – volume: 58 start-page: 817 year: 1987 ident: 10.1016/S0167-5273(02)00186-9_BIB5 article-title: Depression of tissue plasminogen activator (t-PA) activity and rise of t-PA inhibition and acute-phase reactants in blood of patients with acute myocardial infarction (AMI) publication-title: Thromb Haemost doi: 10.1055/s-0038-1645996 contributor: fullname: Gram – volume: 71 start-page: 220 year: 1988 ident: 10.1016/S0167-5273(02)00186-9_BIB24 article-title: Measurement of plasminogen activator inhibitor 1 in biological fluids with a murine monoclonal antibody-based enzyme-linked immunosorbent assay publication-title: Blood doi: 10.1182/blood.V71.1.220.bloodjournal711220 contributor: fullname: Declerck – volume: 80 start-page: 235 year: 2001 ident: 10.1016/S0167-5273(02)00186-9_BIB34 article-title: Platelet hyperaggregability persists even after the improvement of increased blood coagulation and impaired fibrinolysis with the stabilization of symptoms in patients with unstable angina publication-title: Int J Cardiol doi: 10.1016/S0167-5273(01)00515-0 contributor: fullname: Miyamoto – volume: 70 start-page: 327 year: 1988 ident: 10.1016/S0167-5273(02)00186-9_BIB25 article-title: Plasminogen activator inhibitor (PAI-1) in plasma and platelets publication-title: Br J Haematol doi: 10.1111/j.1365-2141.1988.tb02490.x contributor: fullname: Booth – volume: 331 start-page: 417 year: 1994 ident: 10.1016/S0167-5273(02)00186-9_BIB35 article-title: The prognostic value of C-reactive protein and serum amyloid A protein in severe unstable angina publication-title: New Engl J Med doi: 10.1056/NEJM199408183310701 contributor: fullname: Liuzzo – volume: 80 start-page: 881 year: 1998 ident: 10.1016/S0167-5273(02)00186-9_BIB33 article-title: Augmented platelet aggregation as predictor of reocclusion after thrombolysis in acute myocardial infarction publication-title: Thromb Haemost doi: 10.1055/s-0037-1615382 contributor: fullname: Nordt – volume: 24 start-page: 67 year: 1994 ident: 10.1016/S0167-5273(02)00186-9_BIB20 article-title: Effects of captopril therapy on endogenous fibrinolysis in men with recent, uncomplicated myocardial infarction publication-title: J Am Coll Cardiol doi: 10.1016/0735-1097(94)90543-6 contributor: fullname: Wright |
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Snippet | Background: The prognostic value of plasma concentrations of tissue type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and... The prognostic value of plasma concentrations of tissue type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and C-reactive protein... BACKGROUNDThe prognostic value of plasma concentrations of tissue type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and C-reactive... |
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SubjectTerms | Aged Biological and medical sciences Biomarkers - blood C-reactive protein C-Reactive Protein - analysis Cardiology. Vascular system Coronary heart disease Death, Sudden, Cardiac - etiology Female Fibrinolysis Heart Humans Male Medical sciences Middle Aged Myocardial infarction (MI) Myocardial Infarction - blood Myocardial Infarction - complications Plasminogen Activator Inhibitor 1 - blood Plasminogen activator inhibitor-1 (PAI-1) Prognosis Proportional Hazards Models Recurrence Survival Analysis Tissue Plasminogen Activator - blood Tissue type plasminogen activator (t-PA) |
Title | Plasma concentrations of fibrinolytic factors in the subacute phase of myocardial infarction predict recurrent myocardial infarction or sudden cardiac death |
URI | https://dx.doi.org/10.1016/S0167-5273(02)00186-9 https://www.ncbi.nlm.nih.gov/pubmed/12208595 https://search.proquest.com/docview/72052169 |
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