A TRPM7 mutation linked to familial trigeminal neuralgia: Omega current and hyperexcitability of trigeminal ganglion neurons - Gualdani, Roberta; Gailly, Philippe; Yuan, Jun-Hui; Yerna, Xavier; Di Stefano, Giulia; Truini, Andrea; Cruccu, Giorgio; Dib-Hajj, Sulayman D.; Waxman, Stephen G. (Proceedings of the National Academy of Sciences - PNAS, 2022)
Keywords: Alanine; Alanine - genetics; Biological Sciences; Calcium imaging; Calcium ions; Domains; Firing pattern; Gadolinium; Genetic factors; Genetics; Humans; Hydrophobicity; Ion channels; Male; Membrane potential; Mutation; Neuralgia; Neurons; Neurons - physiology; Pain; Protein Serine-Threonine Kinases - genetics; Threonine; Transient receptor potential proteins; Trigeminal ganglion; Trigeminal Ganglion - physiopathology; Trigeminal nerve; Trigeminal Neuralgia - genetics; TRPM Cation Channels - genetics; TRPM Cation Channels - metabolism; human mutations; trigeminal neuralgia; TRP channels; gating current