Brain network dynamics are hierarchically organized in time

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 114; no. 48; pp. 12827 - 12832
• Main Authors: Vidaurre, Diego, Smith, Stephen M., Woolrich, Mark W.
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 28.11.2017
• Series: From the Cover
• Subjects: Adult; Biological Sciences; Brain; Brain - anatomy & histology; Brain - diagnostic imaging; Brain - physiology; Brain Mapping; Cognition & reasoning; Cognition - physiology; Female; Humans; Magnetic Resonance Imaging; Male; Metastasis; Models, Neurological; Nerve Net - anatomy & histology; Nerve Net - diagnostic imaging; Nerve Net - physiology; Neural Pathways - anatomy & histology; Neural Pathways - diagnostic imaging; Neural Pathways - physiology; NMR; Nuclear magnetic resonance; Quantitative Trait, Heritable; Rest - physiology; Task Performance and Analysis; Time Factors; metastates; dynamic functional connectivity; hidden Markov model; resting-state networks

The brain recruits neuronal populations in a temporally coordinated manner in task and at rest. However, the extent to which large-scale networks exhibit their own organized temporal dynamics is unclear. We use an approach designed to find repeating network patterns in whole-brain resting fMRI data,...