Dimeric sorting code for concentrative cargo selection by the COPII coat

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 115; no. 14; pp. E3155 - E3162
• Main Authors: Nie, Chao, 聂超, Wang, Huimin, 王惠敏, Wang, Rui, 王锐, Ginsburg, David, Chen, Xiao-Wei, 陈晓伟
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 03.04.2018
• Series: PNAS Plus
• Subjects: Biochemistry; Biological Sciences; Biotin; Biotinylation; Cargo; Dimers; Endoplasmic reticulum; Fusion protein; Golgi apparatus; Guanosine triphosphate; Oligomerization; PNAS Plus; Protein interaction; Proteins; Regulators; Secretory vesicles; Transport; Vesicles; COPII; LMAN1; proximity-dependent biotinylation; cargo sorting; cargo receptor

The flow of cargo vesicles along the secretory pathway requires concerted action among various regulators. The COPII complex, assembled by the activated SAR1 GTPases on the surface of the endoplasmic reticulum, orchestrates protein interactions to package cargos and generate transport vesicles en ro...