Spatial confinement of active microtubule networks induces large-scale rotational cytoplasmic flow

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 114; no. 11; pp. 2922 - 2927
• Main Authors: Suzuki, Kazuya, Miyazaki, Makito, Takagi, Jun, Itabashi, Takeshi, Ishiwata, Shin’ichi
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 14.03.2017
• Subjects: Biological Sciences; Cells; Cytoplasm; Cytoskeleton; Frogs; self-organization; symmetry breaking; active matter; cytoskeleton; directed flow

Collective behaviors of motile units through hydrodynamic interactions induce directed fluid flow on a larger length scale than individual units. In cells, active cytoskeletal systems composed of polar filaments and molecular motors drive fluid flow, a process known as cytoplasmic streaming. The mot...