Automatic semi-quantification of [123I]FP-CIT SPECT scans in healthy volunteers using BasGan version 2: results from the ENC-DAT database

• Published in: European journal of nuclear medicine and molecular imaging Vol. 40; no. 4; pp. 565 - 573
• Main Authors: Nobili, Flavio, Naseri, Mehrdad, De Carli, Fabrizio, Asenbaum, Susan, Booij, Jan, Darcourt, Jacques, Ell, Peter, Kapucu, Özlem, Kemp, Paul, Varer, Claus, Morbelli, Silvia, Pagani, Marco, Sabri, Osama, Tatsch, Klaus, Tossici-Bolt, Livia, Sera, Terez, Borght, Tierry Vander, Van Laere, Koen, Varrone, Andrea
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.04.2013; Springer Nature B.V
• Subjects: Adult; Age; Age Factors; Aged; Aged, 80 and over; Aging; Basal ganglia; Basal Ganglia - diagnostic imaging; Body mass index; Brain; Cameras; Cardiology; Caudate nucleus; Circadian rhythms; Computer programs; Data processing; Databases, Factual; Dopamine transporter; Female; Handedness; Humans; Imaging; Male; Medicine; Medicine & Public Health; Middle Aged; Neostriatum; Neuroimaging; Nuclear Medicine; Oncology; Original Article; Orthopedics; Putamen; Radiology; Radiopharmaceuticals; Receptors, Dopamine - analysis; Sex differences; Sex Factors; Single photon emission computed tomography; Software; Tomography, Emission-Computed, Single-Photon; Tropanes; Basal ganglia; BasGan software; I]FP-CIT; DAT; Healthy subjects; [; Brain SPECT

Purpose The aim of this study was to assess striatal dopamine transporter (DAT) availability in a large group of normal subjects. Methods The study included 122 healthy subjects, aged 18–83 years, recruited in the multicentre ‘ENC-DAT’ study (promoted by the European Association of Nuclear Medicine)...