Aryl Hydrocarbon Receptor Activation by Dioxin Targets Phosphoenolpyruvate Carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-inducible Poly(ADP-ribose) Polymerase (TiPARP) - Diani-Moore, Silvia; Zhang, Sheng; Ram, Payal; Rifkind, Arleen B. (The Journal of biological chemistry, 2013)
Keywords: Adenosine Diphosphate Ribose - metabolism; ADP-ribosylation; Amino Acid Sequence; Animals; Aryl Hydrocarbon Receptor; Blotting, Western; Cell Line, Tumor; Cells, Cultured; Chick Embryo; Chickens; Dioxin; Enzymology; Gene Expression; HEK293 Cells; Hep G2 Cells; Hepatocytes - cytology; Hepatocytes - drug effects; Hepatocytes - metabolism; Humans; Liver; Molecular Sequence Data; Phosphoenolpyruvate Carboxykinase; Phosphoenolpyruvate Carboxykinase (ATP) - genetics; Phosphoenolpyruvate Carboxykinase (ATP) - metabolism; Poly(ADP-ribose) Polymerases - genetics; Poly(ADP-ribose) Polymerases - metabolism; Polychlorinated Dibenzodioxins - pharmacology; Protein Processing, Post-Translational - drug effects; Proteomics; Rats; Receptors, Aryl Hydrocarbon - genetics; Receptors, Aryl Hydrocarbon - metabolism; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Tandem Mass Spectrometry; TiPARP; TiPARP; Aryl Hydrocarbon Receptor; Phosphoenolpyruvate Carboxykinase; Dioxin; Liver; ADP-ribosylation