Reprogramming cell fates in the mammary microenvironment

• Published in: Cell cycle (Georgetown, Tex.) Vol. 8; no. 8; pp. 1127 - 1132
• Main Authors: Boulanger, Corinne A., Smith, Gilbert H.
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 15.04.2009
• Subjects: Animals; Binding; Biology; Bioscience; Calcium; Cancer; Cell; Cell Fusion; Cell Lineage; Cycle; Humans; Landes; Mammary Glands, Human - cytology; Organogenesis; Proteins; Stem Cell Niche - cytology; Stem Cells - cytology

The capacity of any portion of the murine mammary gland to produce a complete functional mammary outgrowth upon transplantation to an epithelium-divested fat pad is unaffected by the age or reproductive history of the donor. Likewise, through serial transplantations, no loss of potency is detected w...