Expression profiling of precuneus layer III cathepsin D‐immunopositive pyramidal neurons in mild cognitive impairment and Alzheimer's disease: Evidence for neuronal signaling vulnerability - He, Bin; Perez, Sylvia E.; Lee, Sang H.; Ginsberg, Stephen D.; Malek‐Ahmadi, Michael; Mufson, Elliott J. (Journal of comparative neurology (1911), 2020)
Keywords: Aged, 80 and over; Alzheimer Disease - genetics; Alzheimer Disease - pathology; Alzheimer's disease; Amyloid; Autophagy; Autopsy; Brodmann's area; Cathepsin D; Cathepsin D - genetics; Cathepsin D - metabolism; Cognitive ability; Cognitive Dysfunction - genetics; Cognitive Dysfunction - pathology; Cortex (parietal); Cytoskeleton; Defects; Dementia disorders; DNA microarrays; expression profiling; Female; Gene Expression Profiling; Glutamic acid receptors; Glutamic acid receptors (metabotropic); Humans; Hydrolase; Laser Capture Microdissection; Male; microarray; Microarray Analysis; mild cognitive impairment; Neurodegenerative diseases; neurons; Neurotransmission; Parietal Lobe - pathology; Phagocytosis; precuneus; Pyramidal cells; Pyramidal Cells - metabolism; Pyramidal Cells - pathology; RRID; Signal Transduction; Tau protein; microarray; precuneus; expression profiling; mild cognitive impairment; Alzheimer's disease; RRID; laser capture microdissection; neurons