Septicemia after chemotherapy for childhood acute lymphoblastic leukemia in China: A multicenter study CCCG‐ALL‐2015

• Published in: Cancer medicine (Malden, MA) Vol. 9; no. 6; pp. 2113 - 2121
• Main Authors: Zhu, Yiping, Yang, Rong, Cai, Jiaoyang, Yu, Jie, Tang, Yanjing, Chen, Yumei, Wang, Ningling, He, Hailong, Wu, Xuedong, Cheng, Frankie W. T., Sun, Lirong, He, Yingyi, Ju, Xiuli, Tian, Xin, Hu, Qun, Jin, Runming, Pan, Kaili, Fang, Yongjun, Zhai, Xiaowen, Jiang, Hui, Li, Chi‐kong
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.03.2020; John Wiley and Sons Inc; Wiley
• Subjects: Acute lymphoblastic leukemia; Adolescent; Age; Antibiotics; Antineoplastic Combined Chemotherapy Protocols - adverse effects; Bacteremia - blood; Bacteremia - epidemiology; Bacteremia - etiology; Bacteria; Chemotherapy; Child; Child, Preschool; Childhood; Children; China - epidemiology; Clinical Cancer Research; Computer centers; Consolidation Chemotherapy - adverse effects; Consolidation Chemotherapy - methods; Developing countries; Disease control; Drug resistance; E coli; Female; Females; Fungemia - blood; Fungemia - epidemiology; Fungemia - etiology; Fungi; Gender; Gram-negative bacteria; Humans; Incidence; Induction Chemotherapy - adverse effects; Induction Chemotherapy - methods; Infant; Laboratories; LDCs; Leukemia; Lymphatic leukemia; Maintenance Chemotherapy - adverse effects; Maintenance Chemotherapy - methods; Male; Mortality; multicenter study; Original Research; Patients; Precursor Cell Lymphoblastic Leukemia-Lymphoma - blood; Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality; Prospective Studies; Retrospective Studies; Risk Factors; Sepsis; Septicemia; Sex Factors; Streptococcus infections; Studies; China; mortality; multicenter study; septicemia; acute lymphoblastic leukemia; children

Background Septicemia is an important cause of treatment‐related mortality and treatment failure in pediatric acute lymphoblastic leukemia (ALL) in developing countries. A multicenter CCCG‐ALL‐2015 study was conducted in China and factors associated with septicemia and mortality were studied. Method...