Low‐Magnitude Mechanical Stimulation to Improve Bone Density in Persons of Advanced Age: A Randomized, Placebo‐Controlled Trial

• Published in: Journal of bone and mineral research Vol. 30; no. 7; pp. 1319 - 1328
• Main Authors: Kiel, Douglas P, Hannan, Marian T, Barton, Bruce A, Bouxsein, Mary L, Sisson, Emily, Lang, Thomas, Allaire, Brett, Dewkett, Dawn, Carroll, Danette, Magaziner, Jay, Shane, Elizabeth, Leary, Elizabeth Teng, Zimmerman, Sheryl, Rubin, Clinton T
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.07.2015
• Subjects: Aged; Bone Density; BONE MINERAL DENSITY; BONE TURNOVER; Collagen Type I - blood; ELDERLY; Female; Femur - physiology; Humans; Male; Peptide Fragments - blood; Peptides - blood; Placebos; Procollagen - blood; RANDOMIZED CONTROLLED TRIAL; Spine - physiology; Vibration; WHOLE‐BODY VIBRATION; RANDOMIZED CONTROLLED TRIAL; ELDERLY; BONE MINERAL DENSITY; BONE TURNOVER; WHOLE-BODY VIBRATION

Nonpharmacologic approaches to preserve or increase bone mineral density (BMD) include whole‐body vibration (WBV), but its efficacy in elderly persons is not clear. Therefore, we conducted the Vibration to Improve Bone in Elderly Subjects (VIBES) trial, a randomized, placebo‐controlled trial of 10 m...