LncRNA DLX6-AS1 promoted cancer cell proliferation and invasion by attenuating the endogenous function of miR-181b in pancreatic cancer

• Published in: Cancer cell international Vol. 18; no. 1; pp. 143 - 12
• Main Authors: An, Yong, Chen, Xue-min, Yang, Yong, Mo, Feng, Jiang, Yong, Sun, Dong-lin, Cai, Hui-hua
• Format: Journal Article
• Language: English
• Published: England BioMed Central 18.09.2018; BMC
• Subjects: Antisense RNA; Apoptosis; Cancer therapies; Cell cycle; Cell growth; Cell migration; Cell proliferation; Cholecystokinin; Epidermal growth factor; Gene expression; Homeobox; Kinases; lncRNA DLX6-AS1; Lymph nodes; Medical prognosis; Mesenchyme; Metastases; Metastasis; Migration and invasion; miR-181b; Pancreatic cancer; Primary Research; Proliferation; Ribonucleic acid; RNA; Xenografts; Zinc finger E-box-binding homeobox 2; Zinc finger proteins; United States > US; lncRNA DLX6-AS1; miR-181b; Migration and invasion; Proliferation; Zinc finger E-box-binding homeobox 2; Pancreatic cancer

Pancreatic cancer, one of the most aggressive malignancies, ranks the fourth cause of cancer-related death worldwide. Aberrantly expressed long non-coding RNAs (lncRNAs) functioned as oncogenes or tumor suppressors in pancreatic cancer. This study aimed to determine the expression of lncRNA DLX6 ant...