Molecular aspects of Omicron, vaccine development, and recombinant strain XE: A review

• Published in: Journal of medical virology Vol. 94; no. 10; pp. 4628 - 4643
• Main Authors: K, Akash, Sharma, Avinash, Kumar, Deepak, Singh, Sachin K., Gupta, Gaurav, Chellappan, Dinesh K., Dua, Kamal, Nagraik, Rupak
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.10.2022; John Wiley and Sons Inc
• Subjects: ACE2; Angiotensin-converting enzyme 2; Antibodies; COVID-19; COVID-19 - prevention & control; COVID-19 vaccines; CRISPR; Disease resistance; Epidemiology; Humans; Infections; Infectivity; Mutation; Omicron; Pandemics; R&D; recombinant variants; Research & development; Review; Reviews; SARS-CoV-2 - genetics; spike region; vaccine; Vaccine Development; Vaccines; variant of COVID‐19; Viral diseases; Virology; Viruses; recombinant variants; variant of COVID-19; vaccine; Omicron; spike region

The global pandemic of COVID‐19 began in December 2019 and is still continuing. The past 2 years have seen the emergence of several variants that were more vicious than each other. The emergence of Omicron (B.1.1.529) proved to be a huge epidemiological concern as the rate of infection of this parti...