Gamma‐glutamyl transferase and disease course in pediatric‐onset primary sclerosing cholangitis: A single‐center cohort study

• Published in: Health science reports Vol. 6; no. 2; pp. e1086 - n/a
• Main Authors: Berhane, Besrat, Rheenen, Patrick F., Verkade, Henkjan J.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.02.2023; John Wiley and Sons Inc; Wiley
• Subjects: Adults; Ascites; autoimmune hepatitis; Bile ducts; Cholangitis; Clinical outcomes; Cohort analysis; Ethics; hepatic complications; Histology; Hypertension; Inflammatory bowel disease; Laboratories; Liver diseases; liver transplantation; Liver transplants; Original Research; Patients; Pediatrics; Review boards; surrogate marker; clinical outcomes; hepatic complications; autoimmune hepatitis; surrogate marker; liver transplantation

Background and Aims Patients with pediatric‐onset primary sclerosing cholangitis (PSC) are at risk of developing hepatic complications with liver transplantation as only curative treatment. Complications usually occur over many years, underlining the need for reliable surrogate markers to predict th...