Antiviral activity, safety, and pharmacokinetics/pharmacodynamics of tenofovir alafenamide as 10-day monotherapy in HIV-1-positive adults - Ruane, Peter J; DeJesus, Edwin; Berger, Daniel; Markowitz, Martin; Bredeek, U Fritz; Callebaut, Christian; Zhong, Lijie; Ramanathan, Srini; Rhee, Martin S; Fordyce, Marshall W; Yale, Kitty (Journal of acquired immune deficiency syndromes (1999), 2013)
Keywords: Adenine - adverse effects; Adenine - analogs & derivatives; Adenine - blood; Adenine - pharmacokinetics; Adenine - pharmacology; Adenine - therapeutic use; Adult; Anti-Retroviral Agents - pharmacokinetics; Anti-Retroviral Agents - pharmacology; Anti-Retroviral Agents - therapeutic use; Area Under Curve; Dose-Response Relationship, Drug; Fatigue - chemically induced; Female; HIV Infections - blood; HIV Infections - drug therapy; HIV-1; Humans; Male; Middle Aged; Nausea - chemically induced; Organophosphates - blood; Organophosphonates - pharmacokinetics; Organophosphonates - pharmacology; Organophosphonates - therapeutic use; RNA, Viral - blood; Single-Blind Method; Statistics, Nonparametric; Tenofovir; Viral Load; Young Adult