Absence of effect of steady state bempedoic acid on cardiac repolarization: Results of a thorough QT/QTc study in healthy volunteers - Amore, Benny M.; Cramer, Clay T.; MacDougall, Diane E.; Sasiela, William J.; Emery, Maurice G. (Clinical and translational science, 2021)
Keywords: Acids; Adenosine triphosphate; Adolescent; Adult; Antibiotics; Antigens; Arrhythmias, Cardiac - drug therapy; Blood pressure; Cardiovascular disease; Dicarboxylic Acids - pharmacology; Dose-Response Relationship, Drug; Double-Blind Method; Drug dosages; Electrocardiography; Enzyme Inhibitors - pharmacology; Fatty Acids - pharmacology; FDA approval; Female; Healthy Volunteers; Heart Rate - drug effects; Hepatitis; Humans; Hypercholesterolemia; Laboratory animals; Long QT Syndrome; Male; Middle Aged; Mortality; Moxifloxacin; Placebos; Potassium; Young Adult; United States--US