Histological and immunohistochemical comparison of two different allogeneic bone grafting materials for alveolar ridge reconstruction: A prospective randomized trial in humans

• Published in: Clinical implant dentistry and related research Vol. 21; no. 5; pp. 1002 - 1016
• Main Authors: Solakoglu, Önder, Götz, Werner, Heydecke, Guido, Schwarzenbach, Heidi
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.10.2019; Wiley Subscription Services, Inc
• Subjects: Alveolar bone; Alveolar Process; Alveolar Ridge Augmentation; Augmentation; Bone grafts; Bone growth; Bone remodeling; Bone Substitutes; Bone Transplantation; Correlation analysis; Dental Implantation, Endosseous; Grafting; guided bone regeneration; Hematopoietic Stem Cell Transplantation; histomorphometry; human histology; Humans; Immunogenicity; Immunology; Integration; lateral ridge augmentation; Major histocompatibility complex; Original; Osteogenesis; particulated bone allograft; Prospective Studies; Proteins; Skin & tissue grafts; Substitute bone; Surgery; Surgical implants; guided bone regeneration; histomorphometry; particulated bone allograft; lateral ridge augmentation; human histology

ABSTRACT Background Preclinical studies have hypothesized a possible immunological reponse to allogeneic materials due to detection of remnants of potential immunogenic molecules. However, their impact on integration, bone remodeling and immunological reaction after the augmentation procedure is lar...