Novel drug developmental strategies for treatment‐resistant depression - Borbély, Éva; Simon, Mária; Fuchs, Eberhard; Wiborg, Ove; Czéh, Boldizsár; Helyes, Zsuzsanna (British journal of pharmacology, 2022)
Keywords: Animal models; Animals; antidepressant; Antidepressive Agents - pharmacology; Antidepressive Agents - therapeutic use; Antipsychotics; Clinical trials; Depression - drug therapy; Depressive Disorder, Major - drug therapy; Depressive Disorder, Treatment-Resistant - drug therapy; Drug Development; glutamate; Glutamatergic transmission; Glutamic acid receptors (ionotropic); Glutamic acid receptors (metabotropic); Humans; Inflammation; Ketamine; Mental depression; Molecular modelling; monoamine; N-Methyl-D-aspartic acid receptors; Neuroimaging; neuroinflammation; neuroplasticity; Neuroprotection; Neuroprotective agents; Neurotransmission; opioid; Review; Therapeutic targets; Treatment resistance; Tryptamine; neuroinflammation; monoamine; antidepressant; opioid; glutamate; neuroimaging; neuroplasticity