Nonalcoholic steatohepatitis in children: A multicenter clinicopathological study

• Published in: Hepatology (Baltimore, Md.) Vol. 50; no. 4; pp. 1113 - 1120
• Main Authors: Carter‐Kent, Christine, Yerian, Lisa M., Brunt, Elizabeth M., Angulo, Paul, Kohli, Rohit, Ling, Simon C., Xanthakos, Stavra A., Whitington, Peter F., Charatcharoenwitthaya, Phunchai, Yap, Jason, Lopez, Rocio, McCullough, Arthur J., Feldstein, Ariel E.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.10.2009; Wiley
• Subjects: Adolescent; Aspartate Aminotransferases - blood; Biological and medical sciences; Biopsy; Canada; Child; Child, Preschool; Cohort Studies; Disease Progression; Fatty Liver - blood; Fatty Liver - diagnosis; Fatty Liver - pathology; Female; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Liver - pathology; Liver Cirrhosis - pathology; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Medical sciences; Predictive Value of Tests; Prognosis; Retrospective Studies; Severity of Illness Index; United States; Canada; United States; Human; Child; Gastroenterology

Nonalcoholic fatty liver disease (NAFLD) may have distinct histological features in children and adults, but to date limited data are available on the spectrum and significance of histological lesions in pediatric patients. We conducted a multicenter study of children with well‐characterized, biopsy...