Data driven evaluation of healthy volunteer characteristics at screening for phase I clinical trials to inform on study design and optimize screening processes - Deiteren, Annemie; Coenen, Erwin; Lenders, Sabine; Verwilst, Peter; Mannaert, Erik; Rasschaert, Freya (Clinical and translational science, 2021)
Keywords: Adolescent; Adult; Age; Aged; Alanine; Alanine transaminase; Bilirubin; Blood pressure; Body mass index; Clinical trials; Creatinine; Demographics; Drug dosages; EKG; Electrocardiography; Enrollments; Epidermal growth factor receptors; Female; Glomerular filtration rate; Healthy Volunteers; Heart rate; Hemoglobin; Humans; Immunology; Infectious diseases; Laboratories; Liver; Male; Mass Screening - standards; Metabolism; Middle Aged; Patient Selection; Pharmacology; Prothrombin; Pulmonary hypertension; Research Design; Retrospective Studies; Vaccines; Vital signs; Womens health; Young Adult