A preliminary investigation of high retinoic acid exposure during fetal development on behavioral competency and litter characteristics in newborn rats

• Published in: Brain and behavior Vol. 11; no. 10; pp. e2253 - n/a
• Main Authors: Swann‐Thomsen, Hillary E., Mendez‐Gallardo, Valerie, Kollmeyer, Leah R., Hunter, Kira, Brumley, Michele R.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.10.2021; John Wiley and Sons Inc; Wiley
• Subjects: Animals; Animals, Newborn; Behavior; Bladder; Female; Fetal Development; Fetuses; Fitness equipment; Laboratories; Learning disabilities; Meningomyelocele; Mortality; neural tube; Newborn babies; Obesity; Original Research; Pregnancy; Prenatal development; Rats; Recovery of function; Rodents; Spina bifida; Spinal Cord; Tretinoin; United States > US; Idaho; meningomyelocele; neural tube; tretinoin; rats; spinal cord

Myelomeningocele (MMC) is the most common and severe type of spina bifida in which the developing spine and neural tube fail to close during prenatal development. This typically results in a small portion of the lower spinal cord and meninges protruding from the back of the individual, accompanied b...